Entrez gene ID | | 5111 |
Official gene symbol | | PCNA |
Full name | | proliferating cell nuclear antigen |
Aliases | | ,MGC8367, |
Gene summary | | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20pter-p12 |
Gene position | | 5107268 - 5095599 Map Viewer |
Gene orientation | | minus |
Gene size | | 11670 bp |
Gene sequence |
| |
OMIM ID | | 176740 |