Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRAK4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51135
Official gene symbolIRAK4
Full nameinterleukin-1 receptor-associated kinase 4
Aliases,IPD1,NY-REN-64,REN64,
Gene summaryThis gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq]
LocationChromosome: 12   Locus: 12q12
Gene position44152747 - 44183346  Map Viewer
Gene orientationplus
Gene size30600 bp
Gene sequence
OMIM ID606883