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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PCNT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5116
Official gene symbolPCNT
Full namepericentrin
Aliases,KEN,MOPD2,PCN,PCNT2,PCNTB,PCTN2,SCKL4,
Gene summaryThe protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. [provided by RefSeq]
LocationChromosome: 21   Locus: 21q22.3
Gene position47744036 - 47865682  Map Viewer
Gene orientationplus
Gene size121647 bp
Gene sequence
OMIM ID605925