Entrez gene ID | | 5126 |
Official gene symbol | | PCSK2 |
Full name | | proprotein convertase subtilisin/kexin type 2 |
Aliases | | ,NEC2,PC2,SPC2, |
Gene summary | | The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p11.2 |
Gene position | | 17207631 - 17465223 Map Viewer |
Gene orientation | | plus |
Gene size | | 257593 bp |
Gene sequence |
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OMIM ID | | 162151 |
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