Entrez gene ID | | 5136 |
Official gene symbol | | PDE1A |
Full name | | phosphodiesterase 1A, calmodulin-dependent |
Aliases | | ,HCAM1,HSPDE1A,MGC26303, |
Gene summary | | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2q32.1 |
Gene position | | 183387465 - 183007183 Map Viewer |
Gene orientation | | minus |
Gene size | | 380283 bp |
Gene sequence |
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OMIM ID | | 171890 |
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