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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5136
Official gene symbolPDE1A
Full namephosphodiesterase 1A, calmodulin-dependent
Aliases,HCAM1,HSPDE1A,MGC26303,
Gene summaryCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]
LocationChromosome: 2   Locus: 2q32.1
Gene position183387465 - 183007183  Map Viewer
Gene orientationminus
Gene size380283 bp
Gene sequence
OMIM ID171890