Entrez gene ID | | 51564 |
Official gene symbol | | HDAC7 |
Full name | | histone deacetylase 7 |
Aliases | | ,DKFZp586J0917,FLJ99588,HD7A,HDAC7A, |
Gene summary | | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q13.1 |
Gene position | | 48213763 - 48176505 Map Viewer |
Gene orientation | | minus |
Gene size | | 37259 bp |
Gene sequence |
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OMIM ID | | 606542 |
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