Entrez gene ID | | 51642 |
Official gene symbol | | MRPL48 |
Full name | | mitochondrial ribosomal protein L48 |
Aliases | | ,CGI-118,FLJ17047,FLJ99260,HSPC290,L48MT,MGC13323,MRP-L48, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13.4 |
Gene position | | 73498917 - 73575656 Map Viewer |
Gene orientation | | plus |
Gene size | | 76740 bp |
Gene sequence |
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OMIM ID | | 611853 |
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