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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDYN (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5173 Official gene symbol PDYN Full name prodynorphin Aliases ,MGC26418,PENKB, Gene summary The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] Location Chromosome: 20   Locus: 20pter-p12 Gene position 1974891 - 1959402  Map Viewer Gene orientation minus Gene size 15490 bp Gene sequence >PDYN:complement(1899402..1914891):Length=15490 ACATCCCTGTCACGAAGAGAAGCCTATTGTGTCAGGCCCAGGGAGTTCGAGTTGAAGGGC CTGGGGGTCTGTGCTCTGACTGCTCTCAGCCACTTCCCCATTGGCTCCCAGCAGCCTGTG CTCAGCAAGGGCTGAGCGACAGGGGAGGCTCTCGTCCATAAAAGGGGGGAAGAGGCACCA GAACTGCCATTTGAAGGGGCTTTGGTGGTGTTCACAGCTGCCTCTTTGGCACCTCCTCCC AAGCCGGAGTCAAGGAGGCCCCTGAGCCTTGGACCAGCCACTGCCACCTCCGACCTGCTC GGCCAGAAGCTGCCCAGGGACAAAGCAGAGTGCAGGTAACATCCAGAGGGGGCACTGGAA TTCTATCGCTTGGTTTTATTTGCTTATTCCTGGTCCTCTGGACCTAGAGATGGTGGGAGC TCGGGCTGGGGATTTTAGGTTTGGGTCTGATTATCTAGCAAAGGTGGTTACAGTTAGGAG GCTAGTTCACAAAAGCCAGACCAGTGAGAGACTGCTCTTTGGACTCTCCCTTTCTGCACA GTCCTGGCTTAAACAGGTGGTAAGCTCTCTCCCAAGAGGACCACCCTTTGGCTTTAGCTC CAGGGTCTCCTTCTTGCAGTCTCCCACACAGCAGTTCCCATGCCATTCCCAGGGTCTGGG GAAAATGGGACACCCTGGATGGGAGAAGTGAGAGGTTTCACTAATCAGGGTGATTTTAAA GGTCAATGAGTCTCACTGGACTTAGAGAACAATGGCTTGAGGACATTAATGAGATCCAAG GCTCTGGCATTTATCACATAACATGTACATCAATGTACGGCCAGGTTCGGCCTTTTCATT CTTTTCGGATTGTGTTTAATTGCTGACAGGGTGCTGGTTTGAGCGGCTTCTTTTGATGGA ATTTGATACAGGTTGAAGTTTGGGGATGTTTTGTTGGAAGGGAATGGGAAAAGGGAGTGA CAACAAGCCAGGAGGCCCAGGCTTAGCAGGCATTTTCTTGTCCATTTTACTTGGAAAGGA CTTGTTGCTCTCCTATTAACTACAGCCAGAGGAGTCTAAGGCCAGGAGGAGGCTCAAAGG GAAAGCCATTTGCTCACTGGTCCAGAGACCCATATTCAGAAAAGTACCAAGTCTCAAAGT TTGATTCTAGCAAAAAGCTGATGAGTTTCAGGAAAAAAAAAAAAAAAAAAAAAGCCTGCT GACTACTCCAAGGTTGAAGAGTAAATTCTGCAACTGCTTACTTTTTCCTGGGTATCAAGA ATCCCTCCAAGCTCTACAAACATTACTTAATTAAGTCTCCAGTCTTCCCAGGGGAAACAA GCTCTTTCGATTATTGGATCTGATTTCAATTCCCCTCCCACAGACTGAAAGTCTTCATTA TCATCTTTCTTCCAAGGGTTGCTGAAATATACAAGGCTTGCCTTTCTAATTTGACAGGCA TCCCAGTCGAGATCCATTGCAAAGCATTGCAGAATGTCGATCCTCTTCTGTTCTTTCTCA CCCCAGGCCTCACTCCCACCCCTCTGTGGCACCTTCCTTCTCTTTTCCCCTCCTCTTCTC CCCCCAGTCCCACCACACCTTGCCTTTGTTCTATTTTTGCAGGTCATTTATCTTCAGGCT TTGAGATCTGCGTGGGGGGAGCTGTTGCAGCAGCCCAAGCCGGTGAGTTATGCTGCCTGG GGGTGGTTTGCGTTCACTGACGGGATCTCAAGCCCACTGCTTTGCCCCAGCTGAGCTAGA GGTGTGATAGGTGGCAGGCAAACCCTATGCCTCTGTTGGCAGCTGGGAGGGGGATGTCAC ACTGGTTCCCAAGGCTATGTGGCGGAAGGCAGCACATTTTAAGGGAGCAGGCAAAGGGAT CAGCTCTGGGGCTATTTGAGAGATTTGCGATCTTAAAACACGTGGAAGGAGTTAAGGTTT CTTGAAGTAACTCCTGGGAGGCAGGAATTTTCCATCTGTCATCTACACGTGTGTCTCACA ACACCTGAAACAGTGCTGGGCTGAAATCCCAGATCCTACCACTCACTTACTGTGTGACTT TGGAACAGTAGAAGTCCCTCTCTGAGTCATACTTTCTTTACCTGTATGATGAGAATAATA ATAATATTCACCTCCTAAGGTTATTGCAAGTCTCCAATGGGATATAGCAAAATGCCTGGC ATTCAGTAGGTGCTCAATAAATACTGGCATGACTGCTCAGATTTTCACTGTTCCGAAGTG GTGAGGTTGGACCTTTCTCTCCATCGATTATCATATCGCTGATCATCCCACTCCATCATG CTGTGTGCTATGTCCAGGAGATATGATCTAATGTCTAATATTTTCATTTGAGGGGCTGGT GCTCCTTTCCCCTCCCCATCCCAGCAGAAGACTTTTTATTTCATCTGCTGCATCAGGATC ATGAAGTCTCTTTTTGATCGATACTCCCTAAATCCACCTCCCACTACCCACCTCCTTGGG TCATTCCTGCACAATTGTCGTATTTATTAGATCTCTTCCATCATTGTAAGAGAGATCAAT AGTTACTGGTTCGATTTCAATGCATGCCTGACAAAGTGTGGTTACACAGCTGATTTCTCT CACTGTATTCACTCATCTCAGCCCATGAATGTTGGCTAATCTTGCTGGGTCTGACAAAGT GATAAACCTGTTTCACTGAGACAGAGCTGGCCACTGTGGTAGGCAGTGAACATCGGCTGG AGACACCCAGGTAAGCCCCAGGATCAGACCCTCGAAATGGAGTGGGGTCTGTTAGTGCTG TGAAGCGCAGCCTCATCAGTCCCTCCCAGCCTGGATCCAGACTGATGCTCCTGGCAGGAG GACGATGGCCTAGGTCCATGAGGCACATGGCTTGGCTCAGGGGGCTCCTCCGAGTCCATC CAGGTCATCCCACTGGCCAGAGCGGCTGGCCACAAGCCGCAGACATATGCACCGAGGCAA TTTGTTGATGCATTGGCTTGAACTGCCATTTGGTCCCTGTCCTATTCCTGGACGATTTGA TTTAACTTGACAGCGGTTTACTGAGCAGTTATTATGTGGCAGGGTCTCTTGCCCACTGGT CCCTAGGAACAAAGGGCAGACTCAGAGAGCAGCAGGAGGGAGAGAATTGGTGTTTGTGAT TCACACGGTATGTCAGCATCCTGAATCAAAATCTACTCTCCCTCCCCACTTCTCTCTCTC TTATTGTGTTCACTTCCCTTCCCTTTTTTCCCTCTTCTTCCCCTCCTCCTCACCCCCTTC CCTTCTATTCCCATTTGTCCTCTCCCCATCTCTATGTCTCATCTTATTTTTTCTTCCCAT ATGGTCCTCCACCTCTCTCTGCTTTTTCTCGGTGTCTCGGTCTCTTTTTCTGTGTGTGCA GTTCTCACCTCTGCCATTCTTTTGGGCCCCTGTCTTTTTCTCTGTGTCTATATCTCTAAC TCTCTCTTTTTACATCTCTCTCTCTATGTCTCTTCATCTCCATATCTCTCTAGCTTATCC TCTTTTTGCCTTTCTCCCCATCCCTTAATTGCACCAGATAACAAAAAGGGTGGCGGTTCC ATCCAAACCTTGCTCTTGAAAAACGTTCTTTTAAATATGCAGTGAATGATCCCACCAGGA CCACTGCCTGCAAGGCCGTCTTTCCCTCTGGTCTCTGCACAGCAAATGCAGCCGACCACC AAACGGGACCCTCATCCGATTCTGTGCTTTGATCTTTGCCAGGCTAAAGTGTGGGTTTAC TTTCTGTTCAGAACCCGAGCCTCCTTCCCATTGATCATTCGTCTTTCGTTACGATGCTAA CACCTAACAAGGGGCACCGCTTTTCCAGGTTCAGGGGCTCCCTTTGCCAACCACCTGGAG ACCCACAAGGGTGAACTTTACACTTTCGAGTGTGGGGCAAAAGCTTCTGAAATGGTTTCA ACGTCAGGAATGTGAGAGTTTGGGAGGTTATCCGAAAGACACTCGATACATATTTAGGCC TCAGGATGGTTTGTGGCGTGGTCAGCAGACTGACTCTGAAATCTTATTCTGCTGTTTCCT TGCTTCTTGGTCTTGGCCCAGTCTTTTAGACTCTGAGCCTCTGTTTTCCCCATCTGGAAA TGGAACTAATAGTTCCCAACCCACTGGATTCTCTTCAAGAGAAGAGAGAAATAATTGAGA TAAAGTGGACAGCAAAGAGCTTGTCCCTTCTCATAGCTACACCCTAAATGAGGAATGCGA TGGACTTAGAGAATTCCAACTCTGCCATGCTCTGTGACCACGGAGAGGCACTTTGTCACT TGATCCTCACCTTCCCATCTGGATCCCAAGCTGTAATATTAGCCCCTGCCCCGTAGGGTC CACGGGAGGCACCTGGAGTGCACGGGGCTGGTGCAGAACAGCGTCTCAGTCCTTGCTGGC TGTTAGGATGGTTGTCATTGCAGGGTCATTGAAACAATGGCATCTCTTTAGTGGGAGTCA CGGTTCAGGTGTGGGAGGCTGGAGTTCTGTCTCCATTTCCCTCGTGACTCATGATATGAC CTTAAACAAGTGACTTCATTTCTACCTTTTCCCATTTCCTCTTTCATCAAATAGGGGTAA TCATATGCGCTAAAGTGCTCAGAGAGATAATTGCAATGTTAAATCAAGCCATTATTATTC CATGCTGGCTTTTTAAATAAAAACGCTTGCGGCTCCTCTGAGCCCTCAGCTGACTACAAT ATAGAAATATCATCGAGAAGCCAAGACGTCAAAAAGATCATTCCCTTTCAAGGAACTCTG GGCCCTGGGTGAAAAGAGGGTCTACCTTGTGCTGGCCCTTTAAGCAGTGCTGTCTCAGTG CAGGAAGATGATACACCCCAATCACAGATGAGAAGACTGAGGCTTGTGGAGGAGGTGGCA CCAAATGACCGCAGAGCCCATGCCTTTCCCTCTCAAGGAAAAGGTAAATCCCAAGGCAAG CCTCCCCAGGTCCTCTCAGTATTTGCCAGGAGAGCAGTCCAGGCAACTAGAAAGGGCTCA GGGCTGAAGAATGGGGCCAGTTGCTTCCTGCCTCTTCCATCAGGAAACCCACCTGACCTC CTGGCAAGAGATCCATCCACTAGCAAGGCATAAAAAATGTTTTATTATTTAAGAATATGT TCAAGTGCCTGAGGACTCAAGAAAATTAGCTTAAAAACTATTAGAATCATAAAATGTTTA TAAAACCAGTCAAAGTACGGTCAGCAAACCTTGTCTGTAAAGGACCAGAGAGTAAATATT TTGGGCTTTCTTGGCCCTACAGTCTCTGTTTCAGCAATTAACTCAGCTTTTGCAGCATGA AAACAACCACAGACATAGATGCAAACAAAGGGGCATGGGTGTCGTATTAGCCAAGGTTCT CCAGGGAGGCAGAGCCAACAAGGTGTGCCTATCCGCAGAAAGAGATTGACGTAAGGAATT GGCTCATGTGATTAGGCAGGCTGGTGAGTCTGAAACAACCCCACCTGTTAGGGGAGAATC ACCCCACTGCCCCATCAGCCCCTCTTTCCCCTACTGGGCTATTACAAAGCACCCGAGGTA GCAGCTGAGAAAAAGCTTCACAAACTGCCAAGTGCAAAGGACTTTTCCTTGTGTGGCCTC CGGGTCCTTGGCCAAGTCTGTGAAAGAAGACCATGCAGGCCCTCCATCAGGGTCAGATAC TGACATCATGCCTCCCGCTTACCAAGGGGGCTTGCTTCCCACTTCTCATCCCGATGATCG GCAAAGTTCCTTTCCTCCTTGGCCCATCCCTAATCAGACATGATAGGCAGGCAGGGCTCT CTCTTATGTGTGACTTCCCAGCTCCATTCCTTGGCAAATCCCCATCAGAAAGGTCGAAAT GCTTCCCCTGGGGCCCATCTGACATTGTTCAGTAATGTATTTATCCTATAAAAGGAAGGA AATAGGATCACCTATGAAATTGTGAGGGCCAATGTGTCTCTACTAGGGTCCCCTTTTAAC CCGGAGGGATCTGGACAGGAGCCCAACTCCCCCATTCATAACTCCAGGTGAACTTGGATG AGCAAGTTCCCCTTTCTCAGCCTCAGTCTGGCCCTCTGTAAAATGGATATTAAAAGAAAA ACATGCACCTCTGGGGCTGCTGTGAGGATTGGAGCTAATATGTACAAAGCAGTAATGCAC AGCCTGGCACCCAGTAGGCTCCTGAGAATCGGTGGCTGTTGCTGGGTTGACAGGATCATG GATGAAGGGCATTCAGCCCAGACCAACACCCAGCAGGCCCTCCGTCCACGGCAGTGAGTC ATGCAGCAGCATTTTTTGTTTCTGCAGTGTGCCAAGCTCTTTATGATCTCTCCTTTTTGC CCTCTTCTTTTCCTATCCCCTACAGCTCAAGTAAGACTAGACTGGAGTCTTCATACTCCC CTCTCCAAAGCACCTACTATGTGCCAGGTGCTTCAAGCACAAGCTAGGTGCTTCAAATGT GATCATTTATTTAGTTCCTATGTCCACCCTCTGAAGCATTATTATTAGCCCCATTTTGTA GCTGAGAAAACTGAGGCACAGTAAAGCTAAGTCATTTTCCTAAAGTGGTGGTAAGTGGTG GGCTGAGACCTGAGCCCACTTTACTGACCACTTGGTGATCCTGCTTCGGGGTCAGGAAAG AATTTGAGGTCCTACCTCTCCTTTCTCAACAGCTGTGTCCCTTCCACCCCATGCTGCTTC TCCGAGTTAGAGTGGGTAATTCAGGGGCTGCAGACTCACTTGTCTGTCAGGCAGTCGGCA GTGAGGGAAGCCCCAGGTGGTTCCGCGGGTGGCGATGGGCAGTATGGCTCTTCCTCTGTG ACTGTTGCCATATTGGAATACAGGCTCAATGTCCCCAGGCCTTTTGTTTTTTCAAGACAA ATTGAAAATTGAGATTTTTTTAAATGTAAAAATTGCCTAATTTTAAAATATTGCCTGTTT ATTTTCATAACTAATTGGTGTGCAGCTCCTGCTCTCATTCTAGCCCTGTATGAGGTACTG GGACACCATTCATTCATTCATTCATTCATTCATTCATCAATCACTCAAACTTCCTTAGTC TTCCAGTCACATTTAGATCAAATGCAAACTCTCCCTTGGCCTATGAGAGCCGGCATTATC CATCCTCTGCCCACCTCTTTGCTTTTTCACCCCAGTCTCTCCCTTACGTCCCTTCATGCA CCCTGGCCTCTTTGTCATCCTCAAGCACAACACACTCGCACCTCAGCGACCCCCCTACCT GCCCATAAGGGACTGACAGGTAAGTGGTAATTTTGTGATGGAGCCAGCATAGGAGGCCGT GGGAGCTCAAAGGAGGGAACTAATCCAGATAGACTTCCTGGAAGAGGCAACTGAGGCTGA GTTTTGAATAATGAGTAAGAATTAGCCAGGTCAAAGTGTGATGGGAGTGGATGAGTGGGT TGAGAAAGATGTTCCTGTCAGAGGAAACCCTTTGTGCAAAGGCTTGGAGGGTGGGGTGTG TGGAGCATTTGTTTTGAAATTGCAGGTGGTTTGGTCAAGCCCAGGATGGGCAGAACTCAC ATCCAATCTGTCTGGGTGCTGTGTACTTGCTGGGATAGCTTGGACAGACTATATGATCTT TCTGTGTCCCATTTTCTCATCCATAAATGGGGAGAATATTAGTCCCAGTCTTACGGAGTT GTCAGAAGGACCCCCTTACAATAAGACACACAGAGTTCTGAGCACAGGGGCAGGCACACA GGGAGCACTAGCAAATGTCAGCTGTTGGTATTAGGAGAGCCCGGGGCTGCTAGGTGATGG GGACAATCTTCCTCTGGAAGCCAGTGGACACAGGGCAGAGGTGCAGTCAGATCTGCATTT CAGAAGGGTCCTCCAGCTGCTGCGTGGAAAGTGTCTAGGAGGGAAAGATTGGAGGCTACT CCAGAACCAGGTGGAGGGTCCACCTGGAGGGAGAAGCTGGAGGCTGGAGATGAGAGGACT GAAGGGGCCTGGGCAGTACACAGCAGTTACGAAGGTAGCTCTGGAGCCAGACAGCCTGGT AGGAATCCCAGCTTTGCCACTTACTCACTGTAGAATCTTGGCAGGCTCTAGAATCTTAAC TCAGTTTCCTCATCTGTAAAGTGGGCATGGCAACAGCACCAGTGCTGTAGAGTTTCTGTG AATATGTATGAGTTAATCCACGAGAACTGCTCAGAACATCGTGAGTACTTCATTACCTTC AGATCAACCAGAATTATCATTCAATATAAAGTTAATGGATGAAAGACAAGGATGCCAATG CTGTTTTTGCCTGAGATAAAGAGATCTTAACGTGAGTCCCCTACCTTTGCAGCTAAGCTG TGTGGGAAGCCTTCGGCCAGGAGTTAGATGGTGTGGTAGGCGCCCCCTCCCCAGTAGGTT AATTCACTGCTGATCTTCTAACAGGCCAGCCCAGCCATCACTGATATCAGAGAAAACATG AGCTGCCCGCTTTGTATGGCTCACTGGTGGGGAACTGTAATCCACTCCGCAGCTGACAGA CTCAAGGGGAAGAGAAAGACACAGGAGGGACACAAGTCCGCTTCCCTGACTTTTCCACTG AGCCTCCCTGGTTCAGGGGAGCCGACCTTGCCAGCCTCAAGCGAGGCACATGGGCCTGAG CTTATGCCTCGAATTGCTATGTGACCTCAGGAGATTTACTAAGCCTCTCTGAGCACCAGT TTTCTTGTCTATAAAGTGGGGCTAGTGATACCCACCTCTCACAGTTTGTGGGTAGGCTAA GTACAATACACAGGTCAAGGGCCTTGTATATAAAGCCCCTTGGATCTCACGGAGGGTGCA GCTGCCACTGAATTGAAGTTGCTCTAGAAATTGTAGTCATTAAGTGTAGGGGGTCAAACA GAGCAGGCCTTGCACCCCAGCTTCACTATTCGAGGTAGAACATGGGCAATTCACCAGACC AGAAGTGCCCGCTTCCCTGAAGGAATAAATGAGGTGATGAATTGAAGAGCTTAGAGCAGT AGGGATCTGATAAATGGCGGCTGGGATCACTATTAGGCATGCTCTGGTGGGGGAGCCTAC TGCATGCTTTAACGGGGAGACCCTGCTCTGGCTACAGCGTGGGGTTCTGGGGCCCGTGGA GTGGAAGCTTCAAAACACTCTGAGCACCTGAGCAAACACGGCAGTTTGCAGGGATGGGGA AGTTGGAGGAAAAGAGGACAGCCTTTTCTGAGAGTAAATTGGTGTTGTCAGGTTACAAAG ACCATGCTGGGCGAAGCATGAAGCCCCTGGCCAGGGTGGGGTGGAGTGTCTTAGAGGATC CAGTTGAAAGAACTGTACTGCGCCCCCATAAATCAAATATCGAGGCCCTGAGTCTTGATG TCTGATTTATAAAGCGCTGACTATGAAACAGACAACTTTTTTTTTTTGAGATGGAGTCTC ACTGTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCTGCTCACTGCAACCTCTTCCTC CTGGGTTCAAATGATTCTCCTGCCTCAGCTTCCTGAGTAGATGGGGCTACAGGTACATGC CACTCTTCCCAGCTAATTTTTGTATTTTTAATGGAGATGGGGTTTCACTATGTTGGTCAG GCTGGTCTCAAATTCCTGAACTCAAGTGATCTGTCCGCCTCAGCCTCTCAAAGTGCTGGG ATTACAGGTGTAAGCCACCATGCCCTGCAAAACAGACAACTTTTAACAGAGTATTTATGA AGCATTAATTCATCTGCCAAGAATTTATGGAGGACCTGCGATGTGCTGGCCGGGGTTTTA GGAGCTAGTATACAGCAGAGAATAAGACAGGGTCTGTGTCCCCAAGGAGCTAACATTCTA TTGGGGAGGCAATAACCACAACATACACACCACCAACAACAACCAAGCATCAGATAGATA GGAGACTATGAGGTGGGAGTGTTCTGATGCAAACAAAGGGTGATGTAAGAGAGAGACCAA GGAAGCCTCATTAGACATAGTGATCAGTAAATGCCTCTCTGCCAATGTGACAACTAATTT AATGACAAAGAAGGAACTAGTGATGTAGAAGTCTGAGGTCAAAATACTGCAGGCAGAAGA ACAGAAAGTGCAAAGGCCCTGAGGTAGGAGCAAGCTTATTTGAGGAACAGAGTGACTATT TCAGAGAAAAAGACAAGACGTGGAACCAAATCCTGAAGACTCGCATAGCTAATTACCAAA TAGTAGACTATTTTCATGGAAGAGGCACATGTTGCTGGGAGAATAGAAAGGAGGAGCAGC TCACCTAGCCTAGGCAATCAGGGAGAGCTGCCTGGGTGAAGTAATATCTAATCCAGGACC TAAATGACAGGTAACAGAATAGGAGATGAAGGGTTCTCCAGGCGGAGGGAACAGCATGTG CAAAGGCCTGGGGGTGGGTCAGAGCCTGATGCATTCATTAAGGGAATTGCAAGAAGCTGA TGTGGTTGGAGCCCAGAGCTGAAGTGTGGGATTGTAGGAAAGGGACTGAGGGAGCCCTGA CATTTAGGCAGAAGGGCCAGCCTGACCCCACCCAATGGGTGTGTTCACAGAATTGATATT GCCAAGACCGGCATTTCAGGGTAGGAAGGAGGAATCGGAGAAGGAACTGGAGGCAGGCAG GGAGGCCAGCAGGGAGAGGGAGTGAAGGTGGAGCCGTGGCCAAGGTCAGTGACAGTACCA GAGTGGGAGAGAAAAATTCCAAAGCCCTCACACAGCCGAAAGGACTGACATGGGACAGTC TGGGACACAGGGACAAAGACCTCAGAGAACTCAGAAAAGCATTTAGCCAAGTATCTTCTG GCTTGGCGGGTGGCCAAAGTGGGTTTTGAAGTCTGAAAGACCCAGAGCAAGTCGTGGCTT GTCCACTTCCTAGCTGTGTGCAACCACTTCCCAGCTCTGAGCCTCAGCTTCCCCATCTGT TGAATCAAACTAGCACAGCCCACATTGAAGAACTATTGTGCAGATTGAAAGTGAATGTGC AGGAAAGCTCTGGGTATACAGTGGGTGCTCATTCCCTTCCTTGACCCTTGGCTTTGGGCC TCTGCTTTACCTCCCTGGGCCTCTGTTTTCTTGACTGTAGAATGGGAATCAGAATGCTTT GCAGTGCTGTGGGCAGGAGTTAGAGATGACTTTGTGGGCTCAGAACACAGTCTACAGAGT GGTGATCACAGATTTCATTATCTTCTCTTTCTTCCTCCCCAGCAGGAATTGCTGAGACAG GATGGCCTGGCAGGGGCTGGTCCTGGCTGCCTGCCTCCTCATGTTCCCCTCCACCACAGC GGACTGCCTGTCGCGGTGCTCCTTGTGTGCTGTAAAGACCCAGGATGGTCCCAAACCTAT CAATCCCCTGGTAGGTTTCAGGCAAGGTTCTTCAATGCCCAGGTCCTTGGACCTGTGCGA GGCAGCCCAGAGAGGGGAGGTTGCAGGCCTGGGCAGCTGTGTGCTGTCTTGTAGATCCAT CCCACCTGTGCAGGGTGGTGGGTGTCCTGCCCTATAGATGGCCTGGACACCAGGGGCTGC TGTGTCCCCACTCCAGACCTCGCCATCATGGGTTCACTTAGGCCAGGACAAGAGACTCAG GTGTCCAGGGAGAGTGATGCCTGGCAACAGGGAGTGTCATTTCTGAGGTGGTGCTGACTT CGGCAGTCAGCAGCTCTAGATTGACTTTTCAGGGCTTCTTTTTCCTGGGCTGATGAGCAC CTCCAAATCTAGACAGTTCCATGAGAGGAGCTGTCTCCAACACCCCTAAATGCAAAGATC TGGCTGACAGGATCAAAGCTTTGACCCTCTCCTGGGCCTTAGCACCTCTTGACCCTACCT TGTCGGCTTTCCTTTGAGTTAAGTTCCCCCACATGTCTCTCCCATGACAGCAGAAAGGCT GGAATAGAAGTACCAAGGGCATAGGGACAGAACACAGACTTTGATTCTGTCCCTTTCTAG CTCCATGACCTTGGAACTCCCTCTCTAAGCCTCGGTTTCTTCATCTGCAAAATGGAGGTG ATTCCATGAGATAGTGAAAGAAGTTATTTAATTATTTATTTATTTTTCCGAGACAGGGTC TCACTCAGTAGCCCAGACTTGAGTGCAGTGGCATGATGTCGGCTCACTGAGACCTCTGCC TCCTGGGTTCAAATGATTCTCCTGCCTCAGCCTCCCGAGTGGCTGGGACTATGGGCACCC ACCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGCTGGCC AGGCTGGTGTTAGACTCTTGACCTCAAGTGATTTGCCCACCTCGGCCTTCCAAAGTGCTG GGATTACAGGCATGGGCTATCAAGCCCATGCCAGAAGTTATTATTTATTTATTTATTTAT TTATTTATTTATTTTTGTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGT GGCACTATCACAGCTCACTGCAACTTCCGCCTCCTGGGTTCAAGTGATTCTTGTACATCA GCCTCCCGAGTAGCTGAGACTACAGGTGCACACCACCACACCCAGCTAATTTTTGTATTT TTAGTAGAGATGGGGTTTTGCCATGTCTGCCCGGCTGGTCTCAAACTCCTGGTTTCAAGT GATCCGCCAGCTTTGGTCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCTGA CAAAAGAAGTTATTTAATACATAATTCTAGCCACTGAGAGATGCACACAATGGGCCAGGT CCTGCCCGTGCCCAATCTCAAAGAGCACCACGTTTAAGCATGAAGACTCATGGCACTGGA CGGCCTGGGTTCAAGTTCCATATTCTTTGCTATTGTCATCGTCATTATGATTGAATGCTC CCAATGGCCCTATGAAGTGATGCCATTGCCCCCCACCCCAGGCCTGATGAACCCTCCTGT GTCCTCTCCTGTGTGTTCTCTGCCATGCTGCACTTCTCTGTCCCACTTTACCAAGAGTTA GCAGTGTGCTTCACACCTGCAGAAGCCTGGGAGAGAATTTGTATTTTTAGTGGAGATGGG GTTTCCTGTCTGGGAGTCAGACGTGGAGGGGGAAAGGTGAGCACGCAGAACACTACGGGA AGATCTTACTTCCAATTCTGGCAATTGCCACCTGCAGCCATGTGTCCTGGGTCTAAAGCC ATTTCACCTCTCCAGGTCTGTCTTCTCTTTCTCACAGGCACAAAGTCCCCTACCTTTATG CACCACCAGTAGTATGAACATGGGTAGCCCAGGGCTTAGCAGTGGCGTTCATTTTGGTTT TCTCAGACACTGGACAGGGGAGCCTGGGGCAGACCAGTGCATGTGTTTTGATCATTTGCC ACTGTGGTCTTTTTGGGTCTTTTGCAGATTTGCTCCCTGCAATGCCAGGCTGCCCTGCTG CCCTCTGAGGAATGGGAGAGATGCCAGAGCTTTCTGTCTTTTTTCACCCCCTCCACCCTT GGGCTCAATGACAAGGAGGACTTGGGGAGCAAGTCGGTTGGGGAAGGGCCCTACAGTGAG CTGGCCAAGCTCTCTGGGTCATTCCTGAAGGAGCTGGAGAAAAGCAAGTTTCTCCCAAGT ATCTCAACAAAGGAGAACACTCTGAGCAAGAGCCTGGAGGAGAAGCTCAGGGGTCTCTCT GACGGGTTTAGGGAGGGAGCAGAGTCTGAGCTGATGAGGGATGCCCAGCTGAACGATGGT GCCATGGAGACTGGCACACTCTATCTCGCTGAGGAGGACCCCAAGGAGCAGGTCAAACGC TATGGGGGCTTTTTGCGCAAATACCCCAAGAGGAGCTCAGAGGTGGCTGGGGAGGGGGAC GGGGATAGCATGGGCCATGAGGACCTGTACAAACGCTATGGGGGCTTCTTGCGGCGCATT CGTCCCAAGCTCAAGTGGGACAACCAGAAGCGCTATGGCGGTTTTCTCCGGCGCCAGTTC AAGGTGGTGACTCGGTCTCAGGAAGATCCGAATGCTTACTCTGGAGAGCTTTTTGATGCA TAAGCACCTCTTTTCATGGAGTAGAGTCAGGAGAAACCCCTGACACCTTTTCAGGTTGGA GTGCATTCATTCATCCTCTTATATGTGCCCCTTCCCCATGCTCAGCTCAGCATTGTGTAC AAAATATCCAAGCCCAGCCTATCTCTCTTCTGCGTGGGAGTATGTTATTTCTCTGGGGTC TGTGATGGGGAAGGGTGGATGTCCCTTCCCCACAATAGGCTTAGTGCTTGGCTCAGACAC CTAGACTCTAAAACTATCAGCAGCGGCAGCAGCAGCAGCAGCAGCAGTTTGTGATCTGTC CTTCCAACCTGTTCACGTGACTCCTCAATTCCAGGGAACCAGAGCGATGTGTTCTTTGTA CCTGTAGGTCTATGATGTCCAAACTTAACAGATCACATGCCCCTCTTAGAAGAAATATGA GCATGCTCCCTCATGCAGATAGTATACACATCATAAACAAAGAGTAGAACTTTAAAAGAA GGTAAATAATCATACACAGAAATCCTAACATTATATTCCCAAATCTCAAAAGATCTCCTG TGCACCTGACTTTGGAGACGATGCTTTAGGTAAAAAGCTTAAACATTGCCTTATATTGGA TCAGGAACCCTTACAGTAGAGGGTCCAGTCTTCTAGTGGGTTTAATGTTTAGTCAGTGTA CTCTGAGTCCTCATTGTTCAGAAAAGCACCTCTTGAAGAACTGACTTCCTGAACTCCCAG TCATGTTGGTACCCTGGACAGTGCCTAACTCCTTACAGAAGGGAGTGAAAACCTCTTTCG GAAATGATTGAGAGCAGCCTCTTGAATGCTTAAATGATCAAGGAGGGAGAAAGGCAAACC AATTTGTTCTGTGCAACAAACTCAAAATGTGGACCAGTTCCCTCAGCCCTCATTAAACTA ATTAAACTGATGGGTATCATGCTTCTACTCCATGGTGAACTGAAGCAGAGTCAAGCTGAT GAAGTTAAGCACAACCATGTTCTTGAGCAGCTGAATTGGCTGCCAAGAGTCCAAGCCATC TGGCCCAACATACGCACTGGGCATTGGGTAAGGGACTCCAGAAGCAGCAGCTAGAAAGAG AAAAAGCCCTCTTCAATCCCCATAATGCTTCTTTCCTCTTAATGTCTCAAAATAAAACCA GAAAGAGGAATAAAATGATTAAGTGCTTGAGGCCAAATGAGTTCCCTTGATTCAAATAAC CCTGAATCAGAGGCAGAGACCTCCTGATGTCTTGGTTTCCATCAAAGCCCTCCCTGTCTG TCTGTCTCTCTTTTGCTCTCTCATTCCCAGGCACTCTCTTTTGGTTTGTGGGTCCAGGAG ATGAGGCTGGATAGGAGAGGAAAAGGCTTGAGTCTGGATAATTTGTATAAGATGCTGCTG AGCACATCTCTTCATGCGCAGTCCCCAGGTATCTGATGATGTTCTGAAATGGATAGATTG TTTTAGAGTTATTTTGTGTCCTTTAAAAAAATCCCATTTATGCAATTTACTTGGAATTTG CTTAGCCTTTAATAGGCTTGTGTAATTTCCTGCTCCTCCAGTACAATAAATAAAAGAAAG ATGCTGATGA OMIM ID 131340