Entrez gene ID | | 521 |
Official gene symbol | | ATP5I |
Full name | | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E |
Aliases | | ,ATP5K,MGC12532, |
Gene summary | | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants. |
Location | | Chromosome: 4 Locus: 4p16.3 |
Gene position | | 668127 - 666225 Map Viewer |
Gene orientation | | minus |
Gene size | | 1903 bp |
Gene sequence |
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OMIM ID | | 601519 |
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