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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PIK3CG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5294
Official gene symbolPIK3CG
Full namephosphoinositide-3-kinase, catalytic, gamma polypeptide
Aliases,PI3CG,PI3K,PI3Kgamma,PIK3,
Gene summaryThis gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22.3
Gene position106505924 - 106547592  Map Viewer
Gene orientationplus
Gene size41669 bp
Gene sequence
OMIM ID601232