Entrez gene ID | | 5305 |
Official gene symbol | | PIP4K2A |
Full name | | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha |
Aliases | | ,FLJ13267,PI5P4KA,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK, |
Gene summary | | Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10p12.2 |
Gene position | | 23003503 - 22823766 Map Viewer |
Gene orientation | | minus |
Gene size | | 179738 bp |
Gene sequence |
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OMIM ID | | 603140 |
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