Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PIP4K2A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5305
Official gene symbolPIP4K2A
Full namephosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Aliases,FLJ13267,PI5P4KA,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK,
Gene summaryPhosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq]
LocationChromosome: 10   Locus: 10p12.2
Gene position23003503 - 22823766  Map Viewer
Gene orientationminus
Gene size179738 bp
Gene sequence
OMIM ID603140