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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLA2G1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5319
Official gene symbolPLA2G1B
Full namephospholipase A2, group IB (pancreas)
Aliases,MGC119834,MGC119835,PLA2,PLA2A,PPLA2,
Gene summaryPhospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .[supplied by OMIM]
LocationChromosome: 12   Locus: 12q23-q24.1
Gene position120765592 - 120759914  Map Viewer
Gene orientationminus
Gene size5679 bp
Gene sequence
OMIM ID172410