Entrez gene ID | | 5319 |
Official gene symbol | | PLA2G1B |
Full name | | phospholipase A2, group IB (pancreas) |
Aliases | | ,MGC119834,MGC119835,PLA2,PLA2A,PPLA2, |
Gene summary | | Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .[supplied by OMIM] |
Location | | Chromosome: 12 Locus: 12q23-q24.1 |
Gene position | | 120765592 - 120759914 Map Viewer |
Gene orientation | | minus |
Gene size | | 5679 bp |
Gene sequence |
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OMIM ID | | 172410 |
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