Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLA2G5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5322
Official gene symbolPLA2G5
Full namephospholipase A2, group V
Aliases,DKFZp686C2294,GV-PLA2,MGC46205,PLA2-10,hVPLA(2),
Gene summaryThis gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36-p34
Gene position20396701 - 20418394  Map Viewer
Gene orientationplus
Gene size21694 bp
Gene sequence
OMIM ID601192