Entrez gene ID | | 5378 |
Official gene symbol | | PMS1 |
Full name | | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
Aliases | | ,DKFZp781M0253,FLJ98259,HNPCC3,PMSL1,hPMS1, |
Gene summary | | This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q31-q33|2q31.1 |
Gene position | | 190648811 - 190742355 Map Viewer |
Gene orientation | | plus |
Gene size | | 93545 bp |
Gene sequence |
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OMIM ID | | 600258 |