Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PMS1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5378
Official gene symbolPMS1
Full namePMS1 postmeiotic segregation increased 1 (S. cerevisiae)
Aliases,DKFZp781M0253,FLJ98259,HNPCC3,PMSL1,hPMS1,
Gene summaryThis gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q31-q33|2q31.1
Gene position190648811 - 190742355  Map Viewer
Gene orientationplus
Gene size93545 bp
Gene sequence
OMIM ID600258