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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FXYD6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID53826
Official gene symbolFXYD6
Full nameFXYD domain containing ion transport regulator 6
Aliases,-,
Gene summaryThis reference sequence was derived from multiple replicate ESTs and validated by human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD6, is novel and has not been characterized as a protein. Multiple alternatively spliced transcript variants that encode the same protein isoform have been described. RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.]
LocationChromosome: 11   Locus: 11q23.3
Gene position117748145 - 117707693  Map Viewer
Gene orientationminus
Gene size40453 bp
Gene sequence