| Entrez gene ID | | 53828 |
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| Official gene symbol | | FXYD4 |
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| Full name | | FXYD domain containing ion transport regulator 4 |
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| Aliases | | ,CHIF, |
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| Gene summary | | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq] |
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| Location | | Chromosome: 10 Locus: 10q11.21 |
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| Gene position | | 43867092 - 43871783 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 4692 bp |
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| Gene sequence |
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