Entrez gene ID | | 5396 |
Official gene symbol | | PRRX1 |
Full name | | paired related homeobox 1 |
Aliases | | ,PHOX1,PMX1,PRX1, |
Gene summary | | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q24 |
Gene position | | 170633313 - 170708541 Map Viewer |
Gene orientation | | plus |
Gene size | | 75229 bp |
Gene sequence |
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OMIM ID | | 167420 |
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