Entrez gene ID | | 54148 |
Official gene symbol | | MRPL39 |
Full name | | mitochondrial ribosomal protein L39 |
Aliases | | ,C21orf92,FLJ20451,L39mt,MGC104174,MGC3400,MRP-L5,MRPL5,MSTP003,PRED22,PRED66,RPML5, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q21.3 |
Gene position | | 26979801 - 26957968 Map Viewer |
Gene orientation | | minus |
Gene size | | 21834 bp |
Gene sequence |
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OMIM ID | | 611845 |
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