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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for POLR2A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5430
Official gene symbolPOLR2A
Full namepolymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Aliases,MGC75453,POLR2,POLRA,RPB1,RPBh1,RPO2,RPOL2,RpIILS,hRPB220,hsRPB1,
Gene summaryThis gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p13.1
Gene position7387850 - 7417933  Map Viewer
Gene orientationplus
Gene size30084 bp
Gene sequence
OMIM ID180660