Entrez gene ID | | 54534 |
Official gene symbol | | MRPL50 |
Full name | | mitochondrial ribosomal protein L50 |
Aliases | | ,FLJ20493,FLJ21990,MRP-L50, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q31.1 |
Gene position | | 104160919 - 104152249 Map Viewer |
Gene orientation | | minus |
Gene size | | 8671 bp |
Gene sequence |
| |
OMIM ID | | 611854 |
|