Entrez gene ID | | 5454 |
Official gene symbol | | POU3F2 |
Full name | | POU class 3 homeobox 2 |
Aliases | | ,BRN2,OCT7,OTF7,POUF3, |
Gene summary | | POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM] |
Location | | Chromosome: 6 Locus: 6q16 |
Gene position | | 99282580 - 99286666 Map Viewer |
Gene orientation | | plus |
Gene size | | 4087 bp |
Gene sequence |
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OMIM ID | | 600494 |
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