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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MED1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5469
Official gene symbolMED1
Full namemediator complex subunit 1
Aliases,CRSP1,CRSP200,DRIP205,DRIP230,MGC71488,PBP,PPARBP,PPARGBP,RB18A,TRAP220,TRIP2,
Gene summaryThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q12-q21.1
Gene position37607527 - 37560538  Map Viewer
Gene orientationminus
Gene size46990 bp
Gene sequence
OMIM ID604311