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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPBP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5473 Official gene symbol PPBP Full name pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Aliases ,B-TG1,Beta-TG,CTAP-III,CTAP3,CTAPIII,CXCL7,LA-PF4,LDGF,MDGF,NAP-2,PBP,SCYB7,TC1,TC2,TGB,TGB1,THBGB,THBGB1, Gene summary The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. [provided by RefSeq] Location Chromosome: 4   Locus: 4q12-q13 Gene position 74853907 - 74852156  Map Viewer Gene orientation minus Gene size 1752 bp Gene sequence >PPBP:complement(15062823..15064574):Length=1752 ACTTATCTGCAGACTTGTAGGCAGCAACTCACCCTCACTCAGAGGTCTTCTGGTTCTGGA AACAACTCTAGCTCAGCCTTCTCCACCATGAGCCTCAGACTTGATACCACCCCTTCCTGT AACAGTGCGAGACCACTTCATGCCTTGCAGGTGCTGCTGCTTCTGTCATTGCTGCTGACT GCTCTGGCTTCCTCCACCAAAGGACAAACTAAGAGAAACTTGGCGAAAGGCAAAGGTAGA GGCCCTGCTTCTCTGCACTTGTTGCTGCTTCTGCTACACCTGTCTCTGGGGTAAAGACTA GCTTGGTGCCTTTGGGGCTGGAGAGGGCCATTATACCAATAACTCCAATTGGAGGAGACA CACAGGGGGGTCACTTCTCACTTCTTGTGTGCTGGGCAATCTTCTGGGCACTTTACTAAA GCGTTACAGATCATATTCACAATGGCTTTATGAGAGAGGTACAATTGCCCTCAATCTGCA AATAAGAGACCTGAGGAAAATATTCATGACCACCAATAGGTCACATTTTCTACCCTAGAG GAAAGTCTAGACAGTGACTTGTATGCTGAACTCCGCTGCATGTGTATAAAGACAACCTCT GGAATTCATCCCAAAAACATCCAAAGTTTGGAAGTGATCGGGAAAGGAACCCATTGCAAC CAAGTCGAAGTGATGTAAGTTGCTGTTTCTGTGCTATTGCCTTATCAGAGAAACCCTCTA CCTCCATCCACATATGCACTCGTTTCCTCCAGTCTCATGGATTAGTTCTGATATTCAGAT CAGGACACCCACAGATAACCCTGTTCTCTTTTGCAGAGCCACACTGAAGGATGGGAGGAA AATCTGCCTGGACCCAGATGCTCCCAGAATCAAGAAAATTGTACAGAAAAAATTGGCAGG TGATGAATCTGCTGATTAATTTGTTCTGTTTCTGCCAAACTTCTTTAACTCCCAGGAAGG GTAGAATTTTGAAACCTTGATTTTCTAGAGTTCTCATTTATTCAGGATACCTATTCTTAC TGTATTAAAATTTGGATATGTGTTTCATTCTGTCTCAAAAATCACATTTTATTCTGAGAA GGTTGGTTAAAAGATGGCAGAAAGAAGATGAAAATAAATAAGCCTGGTTTCAACCCTCTA ATTCTTGCCTAAACATTGGACTGTACTTTGCATTTTTTTCTTTAAAAATTTCTATTCTAA CACAACTTGGTTGATTTTTCCTGGTCTACTTTATGGTTATTAGACATACTCATGGGTATT ATTAGATTTCATAATGGTCAATGATAATAGGAATTACATGGAGCCCAACAGAGAATATTT GCTCAATACATTTTTGTTAATATATTTAGGAACTTAATGGAGTCTCTCAGTGTCTTAGTC CTAGGATGTCTTATTTAAAATACTCCCTGAAAGTTTATTCTGATGTTTATTTTAGCCATC AAACACTAAAATAATAAATTGGTGAATATGAATCTTATAAACTGTGGTTAGCTGGTTTAA AGTGAATATATTTGCCACTAGTAGAACAAAAATAGATGATGAAAATGAATTAACATATCT ACATAGTTATAATTCTATCATTAGAATGAGCCTTATAAATAAGTACAATATAGGACTTCA ACCTTACTAGACTCCTAATTCTAAATTCTACTTTTTTCATCAACAGAACTTTCATTCATT TTTTAAACCCTAAAACTTATACCCACACTATTCTTACAAAAATATTCACATGAAATAAAA ATTTGCTATTGA OMIM ID 121010