Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPIA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5478
Official gene symbolPPIA
Full namepeptidylprolyl isomerase A (cyclophilin A)
Aliases,CYPA,CYPH,MGC117158,MGC12404,MGC23397,
Gene summaryThis gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p13
Gene position44836241 - 44842716  Map Viewer
Gene orientationplus
Gene size6476 bp
Gene sequence
OMIM ID123840