Entrez gene ID | | 5478 |
Official gene symbol | | PPIA |
Full name | | peptidylprolyl isomerase A (cyclophilin A) |
Aliases | | ,CYPA,CYPH,MGC117158,MGC12404,MGC23397, |
Gene summary | | This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7p13 |
Gene position | | 44836241 - 44842716 Map Viewer |
Gene orientation | | plus |
Gene size | | 6476 bp |
Gene sequence |
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OMIM ID | | 123840 |
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