Entrez gene ID | | 54926 |
Official gene symbol | | UBE2R2 |
Full name | | ubiquitin-conjugating enzyme E2R 2 |
Aliases | | ,CDC34B,FLJ20419,MGC10481,UBC3B, |
Gene summary | | Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9p13.3 |
Gene position | | 33817182 - 33920401 Map Viewer |
Gene orientation | | plus |
Gene size | | 103220 bp |
Gene sequence |
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OMIM ID | | 612506 |