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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PNPO (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 55163 Official gene symbol PNPO Full name pyridoxamine 5'-phosphate oxidase Aliases ,FLJ10535,PDXPO, Gene summary The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq] Location Chromosome: 17   Locus: 17q21.32 Gene position 46018889 - 46026674  Map Viewer Gene orientation plus Gene size 7786 bp Gene sequence >PNPO:11293041..11300826:Length=7786 CATTGGCTCCGAGGACTTAGGACCTGTTAGCTTGGTTGGGCGACTGGCAAATCCTTCCTT CCCCGGGGTAGAAGTCCAGGGTGAGAAATTGGTTCCGAACTCAAAGGAACCCAGTGCCGG GCCACAGCCGGGTCACGTGGCCGGCGGCCCCCCATGACGTGCTGGCTGCGGGGCGTCACG GCGACGTTCGGGCGACCTGCCGAGTGGCCAGGCTACCTCAGTCACCTGTGTGGTCGCAGT GCTGCCATGGACCTGGGACCCATGCGCAAGAGTTACCGCGGGGACCGAGAGGTGCCGCCG CTAGGGCCAGGCCTCCTGCAGGGGCGGGGGAAAAGGGGTCCCCGGAGTCATCTACAGCGG GGAGGGGAGTAGTAGGAGCCCCTCGGGGCTTCTGGGGCCACCCGGTGGGGCAAGGAGGTT TGAGGATCACCCCCCGTGGGAAAAGGGGGCTTCAAAGACATCCCACCAGGGGAGGAGTTC CGGGGAAACGCAAATGAAGATGGGTTCAAAAGGCAGCCTTTCGTAATGGGTAAGAGCTCG AACTTTGGAGCCTGCCTGGGTTGGAATGTTTAATGTATCTGGGCCTCAGTTTCCTCATCT GGGAAGTGATAGTATCTGCCTCACGGGGATGTTATGGTCTAAGATGTTTGTAAAGTGCTT AGAACCCTGCTACTCGACAGGTAGCAAGGTCAAATAACTTGCTCAGTCCCACAGCTAGTG ATGAATGAATCGGGGTTTCATGTGATGGATGTCAGGACTGTGCTGGGCCTCCCTCAAGGG CGGGGGAAGAGGGGTCCTCGGAGTCATCTACTGGGGGGAGGGGAGTAGGAGGAAACAGCC CCTCAGGGCTTCTGGGGCCACCCCCTGGGGCAAGGAGATTTGGGGGTCACCCAAACCTCC TTGTGCCAGGTGGGCATGGTCATGGGCCCCTCTTTAGGTGGGTACAGTGACAAACAGCTT ACAAACTGTTTGACAAAAAAGTAAGTGGAATATGGGGGAAGGGGACTAGCTCGGGGAGGA GGGGAGGAGAAAGCTCTTAGCTTACTGCCTTCAGTACTTTCTGCTGACCACTGGGAAGTT CTTTTCCTTTTCGCTCCTCAGGAGGGGAACCAAGAGAACCTTTTAGGAATTGGGGTCCAG GGCCCTGGTTGCCAAATCTGGTTGCATGTGGGCATTTCTAGAAACGCTTGTTTAAAATGC AGTTTTTCCAGCCTGGGCAACATAGTGAGACCCTGTCTCTACAAAAAATTAAAATTAGTC GAGCATGTTGGAGCGTGCCTGTAATTCCAGCTACTTGGGAGGATGAGGTTGGAGGATTGC TTGAGCTCAGGAAGTTGAGACTGCAGTAAGCCGAGATCACACCACCGCACTCCAGCCTAG GTGACAGAGTGAGACCCTGTCTAAAATAAATAAATAAATAAATAAAAATGCAGTTTTTGA TGAAGCCTCAGACCTGCTGAATGAGAAATTTTGGGGGTGGAGCCCAGAAAGTTTTTTTTA TGCTCCCCAGGTGATTCTGATGCACAGACAGTTTTGACACCCATGACATGTAACCCTGAT TTATCCATCACTAGCTGTGGGACAGCAAGTTGTCTGAGTTTTTATGCCTGTTTCCTCACC TGTAAAATGGGGCACAGAATCTTCTTACTGCATACTATTTCTTATTTTAAGGTCATTGTC ATGAGGACTAAATGAGTTGATTTTTGAAAAGTGACTAGAACAGTGCCAGGTCCATAGTAA GCACTATATATGTTTATTAAATGAAATAAATCTCCTTTCCTAGGCATTTGAGGAGACTCA TCTGACCTCCCTTGACCCAGTGAAACAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTG TCCTGACATAGGGGAAGCCAATGCCATGTGTCTGGCTACCTGCACCAGGTGGGCATGGCT GTGGGCCCCTCTTTGGGTGGATACATATGAACTAGGAAGCTTATGAAGCTCTCTACTCTG GATGCCAATTTTATGGTTCCAGCTCTGTTATTAACATGCTCTGTGGCTTTAGGCAAGATA CTTGTCCTCTCTGGGCCTGTGTCCTTACCTATAAACCAAAGACCAGGCCACAAAATTACA TTTCAGTGATAAAAATGCAGTGCCTTGTTCATTTCTGCCCTTGATACATCCACACACAAC CCCTTGCCTCCCTCATCTCCCCATCTACCCAAGCCCCGTCTGCCATTCAGGAGCTACTTC TCCTGGTGAAGCTCTGTCTCTCTCTCGAAATCTAGCACAGTGCTTGACTATATCATTCCT TTGACAATCATATGCCCTTTGAGACATCACTTGTATTAGCCTGTTATTCAATTCTCCTCG ATAAAGTGTAAGGCCTTGTAGCCAGTGCTCTTGTACTGTGCGAGTGGATATCTCCCAGAG CTCTGAGCAGAGGGGCTGATCTCATAGCACCACTGTGATCCCGAAGCATTGGATGATTGC ATTATTGTTAGTCCCTGCCCTTAGGGTCTTATGAATTTGCTAGGGCTGTCTTAACAAAAT ACTGTAGACTGGATAGCTTAAACAACAGGAGTTTATTTCCTTATAGTTCTGGTGGCTGGA AGTCCAAGATCAAGGTGCCATCAGGGGTGGTTTCTGATGAGGCCTCTGCTTGGGGTTTGC AGACAGCTACTTTTTACCATGTCCTCACACTGCCTTTCGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTTGTGGAGGGCAAGGGAGGTGGTTCTGAAGTGTCTCTTCTCTTACAG TGACACCAGTCCTACTGGATTAGGGCCCCACCCCTATGACCTTACTTAACCTTAATTACC TCCATAAGGTCCCCTTCTCCAAATACAGTCACATTGGGGTTTAAGGCTTTAACATAGGGG TTTGGGGTGACACAATTCAGCCCATAACAGGGCCCCAGGCTGTGGTGTCATACCTCTAGG ACAAATCCCCAGGAGCACATGGGACGGGGTAGCCTGACAGCCCAATAAAGGGGGTGCAGC TGGAGGGGGTGCTGAGACATCCTTTGGGGAGAGGGACTATAGCCAGAACATTGAAGCAGA CTCTGACCACAGTGCTCTGCTCTTTGCTCCTAGAGATGGAAAACCCTCTGCTCGCATGTT GCTGCTGAAGGGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAA AGGAAAAGAGCTGGTGGGTGAAAAGAGCTAGTAATCTTTCCCAGGGCCTGCAGGGTTTGG CTCTTGCTTCCTCAGTCACCTTCTTATGCCACCCCACCCCCCCAGTCTACTTGCTCTCTG TGTGCAGGTGCCCTCCTGCCATGAGGCCTTGGCACTTGCTGTGCTCTTTGCCATAAATGA ATGAATGCACTTTCTAACCAGCCTCACCCCATCAGCCATGACCTGTTCCTTCAGATCTCA GCCCACATGTTACCTCCTCAGGAAGGCCTTCCTTGACTCTCACTCAGACTCAGCCCCTCA TGCTGTTTGCTGCCATTATAACTTGCAACTTTCTTTTTTGTCTTCTTCTTCAGTTTGTAA CTGAGCATTTGTTTGGGTGATTATGTAACTGATATTTGTCTCCTCTGCTCAACAGTAAGC TCTGTAGGAGTGGAGGCTGCTCTGTTTTATCTCTGCTGTATCCCCCGCACGTCTCCTGTT GTCAGACCCAGAGTGGGCACTTCGCGTGCATTCAATGAATGAATCCAAAATGAGTAAACC TCCCTGAGTCCATGCCAGCCAAGCATGCATTTCTCAAGACTCACAAATCTGTGGGTGAGA GAAATCACCCAGTCTCACTTTGGAGTCCGACTGGCTTAAACTTAGCTCCACCACTTCCTG CAGGAACTTGGGCACGTGACTTAGCCTGTCTCTGTGTCTGTGACAATAGGCCTACTTTTG AGGGTTTAAATGAGCTCTTACGGTGGGTGCATCTGCTGTGGGCCTGCGCACTACAGCTCT CCTGCCTTTTCCCTGCATGCCGGAGGCCTCCTCTCCCTGTCCTGATGGCTGGCTGTGGAT TCTCTTTTACTTCTAGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACT TAACCGTCAGGTGAGTGAATTTTCCCAGGACAGCCTGGGATGGGCTGGGTTGGCAGGGCC TGAGTTTATGGCTACGTCTAGCGAAGGTCCCCAGACTGGGCAAACATCCCAGCTGGGCAC TCTGCCTCTAAAATAGCCCTCAGTTAGTTGGAGCCAAGAGTGGTGGGGCAGCCGATCGAA CAGAGAGGAACGGGGCCTGTGCTGGTAGGGAGGGCAGGTGGCATTTAATGCCATTCACCC AGAGCCATCCCTGAGCAGGTGCGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAG GCTGAGTGCTACTTCCACTCCCGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCAC CAGAGTTCTGTGATCCCTGATCGGGAGGTGAGTGGAGCTCCGCTGTAGTCCTCCAGGTGG TGGAGGCTTTGGCTTATCCCCAGAAGCTGTCCCCAGGAGATGCCAGGAGATGTCCCCAGG AGATGTCCTCTCTCTCCAGCCCAGTGAAAACAGTGAAAAGGACAGTGAGAAGGGAAAGTG GGGGTAGGGAGAGGGGAAATAGGCCTCCTCTGTCCATCTGGCCATCCTGTTGACTGCTCC TGGAGGACAGAGGCCAGTCTGCTCTGCTCACCCATGTCCCCAGCACATATCCCCAGGAAG TCCTTGTTAATGAATCATTGACTGGGCCTGGCCCTTCTTCTAACTCTTCCCCCTGGACAG TATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTGCCCAAG CCAAAATCCTGGTGAGTGACATCTGGTAGTCCTCTAGAAAGGGACACCAGGCCCCTGTGT TTACTTGAAGCCACCTGCCTGGGGAATCACAGATCTCCTCCTCCCTGGCCACCCTTGTCA GATGCATCCCAGCAACTTCCTTCAAGAGGCCCTGGGATGAGGGGTGAGGGTGGGAGAGTG ACCTGGCTAGAAAACTCCACAGAGCACTGAAACCTCTGCTTCTCCTTATAGGGGTGGCTA TGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAAGGTCAAACCAACCGCCTGCATGACCG GATAGTCTTTCGGCGGGGCCTACCCACAGGAGATTCCCCTTTGGGGCCCATGACCCACCG CGGGGAGGAAGACTGGCTCTATGAGAGACTTGCACCTTAACTCTGGGACCTGCTGGCCCA GAGTGGAGCTAGGGCTAGGTGTCAAGAGAGGGTGTGGGATTGGGACCCAGGCCCTTCTTT CTAAACTCAACCCATTTCCCTCCCTACCCCTTATCTTCAGGACTCTTCAGAGCTAATCCT CTAAGTTCTCTGTACTCAGTTGGTTCTCAGTTAGCTGGTCAAGTGGAGTGTAATGGTGGC GTAGAGAATCACAAATGGAAAATAATTCCATAATTATTTTTTTGACCTTGCCTATGATTG ATTAGGATAGCTCCCTCTAGGGGTAGCAGCCGGTGTGACTCCCTTTCTGGTGACAGACAG GGCCCCAGCAGCCCTGTCTGTTACCATGTGAGTCATACTGGCCAAAGCTTAGTCCTAGCA TATGCACCTGAGCCAACCTGGCCAATCAGATTGTTTTGTCAATAATTTGAAATTTGAACT GGAGAGATCCAGAACCTTGGGAGTCATTAAAGCCAAGTCATTCATAGCAGCCAGGAAACA ATAGGAACCAAAAGCCTCTGCCTGCTGCTATTGCAATTCCCAGGATCTCTCCTTCCCTGG ATCCCTCCCTCCCAGGTCTGGGCTGTGCAGTTCCTCCCCCTGCCTTAAAACACCCCACTA TCTCTGTAAAGTCTCTCTCTCTCTTTTTTTTTTTTTTACTTAATCTAGCTAGAATCTATT TCTGTTGATTACAACTTAACTAACTCATTTACGGATAGGACTTTTTTTTTTCTTTTTTTC TTTTTTCTTTTCTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTG CAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGC CTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACGCCACCACACCCAACTAATTTTTGT ATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATTGTCTCCATCTCTTGACCTT GTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCC AGCGAGACGGGGTTTCATTATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTAAAGTGAT CTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCACGCTTGGCCG GGATAGTATATTTTTATAGCACTTCCCCTACTGATTGCTGCCTTCTCTGTGGCTACAAGG GACCCACAGAATTACAGGGAAGTTACAGGGAAGCAGGTTTCATCTCAATATTGGGAGAGA TTTCAAACAATCACACCTGCCTGAGAAGGAGTGGGCTGTCACTAGGAATTTTTATTCCCA GTCCGTCAGGAATTTTGTAGAAGGGCTTCATGTGCTGGTACCAATAGGACAGGAAGATTT TAATCAGCTTTACTATCTATGTTTTTTTATGGAAACTGTGTGTATGTATACATACATTTT CCAAAAAGAAAAATTAAATGATTATAGAGATTATGTTTTTCAGACTACTCACGTATCTGC TTTTCTTACTCCCCACCTCTGCTGATAATTCCTAGTTCATTGGTTTTTCCCCCACACTGG AATTACCTGGGGAGCTTAAAAAACCCTGATGCCTGGGTCCCACCCTCAGAGATGATTGAA CCAGCCTGGCCAGCATGGCAAAACCCTGTCTCTACTATGATATGAATGCAGCCTGGGCAC TGGGAAATTTAAAAACTCCCCAGATAATTCTGTGCAGCCAAGGTTGAGACCTCCTAGTCT AGAGCTTTGCTATACACAGGGTGGTCCACAAGCCAGGAGCATCAGCATCACTTGGCAGCG CCTTAGAGATTCAGACCCCAGACCCACTGAATCTGACCCTGCATTTTCACTAGACCCCAG GTGATCAGCTGCACTAGACTCAACCTCTAAACCAAGACCTCCCACCCTCACAGTCTATGA TCCTTTAGTGACCCTCAGCTGAGTCCTGTGCTGAACTGTGTTTGTTCTCCTTGAGCACAT GCCCGCTAACCAGGGACAGACTGGATGAGCAAGCAACCTGCTGGCTATGGAGAAGAGCCA GGCTGGGTAAATGTTTGCTGTGACTAAGCCAGGATCAAAGAACTGCCTGTTGCTTGCACT GGCTGGCACTGAGCTTGCCACTCTGTGAACTGTGCTTCCTTCCCCTGCATGGACCTGTGC CTCAGTCACTATTATCCGCAGGCCTTCTCCAAGGGCAGCCCTCTCCTTGTTTATCCCTCT TAAGCCTGCGTGCAGGAAGGCACATTAACCCTGTGGCCCCCTGCAGGCAGGAGGGTGTTG GGTGCCCTTACCTACCTTGCCCTTTTTCTTGTACCGTAGGCTGTGCCGTTTATGAGTAAG TGATGTGTGTCTGTGTGTGTGTCTAGAAGTGCTGCACTCACCTTGTGTTATTGGAGGTTG TGTAACCCCCTAGCTTTGAGCCTGGTCTCAGATGTTCCTTTTCCGTTCTCTGTCCAGCCG TTACCGCCCCCAGTCTGTAATAAAAGCCTATCAGCCGTGCACTTTA OMIM ID 603287