Entrez gene ID | | 5546 |
Official gene symbol | | PRCC |
Full name | | papillary renal cell carcinoma (translocation-associated) |
Aliases | | ,MGC17178,MGC4723,RCCP1,TPRC, |
Gene summary | | This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. |
Location | | Chromosome: 1 Locus: 1q21.1 |
Gene position | | 156737274 - 156770609 Map Viewer |
Gene orientation | | plus |
Gene size | | 33336 bp |
Gene sequence |
| |
OMIM ID | | 179755 |