Entrez gene ID | | 5552 |
Official gene symbol | | SRGN |
Full name | | serglycin |
Aliases | | ,FLJ12930,MGC9289,PPG,PRG,PRG1, |
Gene summary | | This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q22.1 |
Gene position | | 70847828 - 70864567 Map Viewer |
Gene orientation | | plus |
Gene size | | 16740 bp |
Gene sequence |
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OMIM ID | | 177040 |
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