Entrez gene ID | | 55540 |
Official gene symbol | | IL17RB |
Full name | | interleukin 17 receptor B |
Aliases | | ,CRL4,EVI27,IL17BR,IL17RH1,MGC5245, |
Gene summary | | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21.1 |
Gene position | | 53880577 - 53899827 Map Viewer |
Gene orientation | | plus |
Gene size | | 19251 bp |
Gene sequence |
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OMIM ID | | 605458 |