Entrez gene ID | | 55655 |
Official gene symbol | | NLRP2 |
Full name | | NLR family, pyrin domain containing 2 |
Aliases | | ,CLR19.9,FLJ20510,NALP2,NBS1,PAN1,PYPAF2, |
Gene summary | | NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q13.42 |
Gene position | | 55476652 - 55512510 Map Viewer |
Gene orientation | | plus |
Gene size | | 35859 bp |
Gene sequence |
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OMIM ID | | 609364 |
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