| Entrez gene ID | | 55717 |
|
| Official gene symbol | | WDR11 |
|
| Full name | | WD repeat domain 11 |
|
| Aliases | | ,BRWD2,DKFZp434L1715,DR11,FLJ42531,WDR15, |
|
| Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq] |
|
| Location | | Chromosome: 10 Locus: 10q26 |
|
| Gene position | | 122610687 - 122669038 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 58352 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 606417 |
|
|
|
