Entrez gene ID | | 55764 |
Official gene symbol | | IFT122 |
Full name | | intraflagellar transport 122 homolog (Chlamydomonas) |
Aliases | | ,SPG,WDR10,WDR10p,WDR140, |
Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q21 |
Gene position | | 129158968 - 129239191 Map Viewer |
Gene orientation | | plus |
Gene size | | 80224 bp |
Gene sequence |
| |
OMIM ID | | 606045 |
|