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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HDAC8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55869
Official gene symbolHDAC8
Full namehistone deacetylase 8
Aliases,CDA07,HD8,HDACL1,RPD3,
Gene summaryHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: X   Locus: Xq13
Gene position71792953 - 71549366  Map Viewer
Gene orientationminus
Gene size243588 bp
Gene sequence
OMIM ID300269