Entrez gene ID | | 56000 |
Official gene symbol | | NXF3 |
Full name | | nuclear RNA export factor 3 |
Aliases | | ,-, |
Gene summary | | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq22-q23 |
Gene position | | 102348022 - 102330749 Map Viewer |
Gene orientation | | minus |
Gene size | | 17274 bp |
Gene sequence |
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