Entrez gene ID | | 5638 |
Official gene symbol | | PRRG1 |
Full name | | proline rich Gla (G-carboxyglutamic acid) 1 |
Aliases | | ,PRGP1, |
Gene summary | | This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp21.1 |
Gene position | | 37208528 - 37316548 Map Viewer |
Gene orientation | | plus |
Gene size | | 108021 bp |
Gene sequence |
| |
OMIM ID | | 604428 |
|