Entrez gene ID | | 5651 |
Official gene symbol | | TMPRSS15 |
Full name | | transmembrane protease, serine 15 |
Aliases | | ,ENTK,MGC133046,PRSS7, |
Gene summary | | This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q21|21q21.1 |
Gene position | | 19775970 - 19641433 Map Viewer |
Gene orientation | | minus |
Gene size | | 134538 bp |
Gene sequence |
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OMIM ID | | 606635 |
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