Entrez gene ID | | 56624 |
Official gene symbol | | ASAH2 |
Full name | | N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 |
Aliases | | ,BCDase,HNAC1,MGC129777,NCDase, |
Gene summary | | Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM] |
Location | | Chromosome: 10 Locus: 10q11.21 |
Gene position | | 52008370 - 51947000 Map Viewer |
Gene orientation | | minus |
Gene size | | 61371 bp |
Gene sequence |
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OMIM ID | | 611202 |
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