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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ASAH2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID56624
Official gene symbolASAH2
Full nameN-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
Aliases,BCDase,HNAC1,MGC129777,NCDase,
Gene summaryCeramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM]
LocationChromosome: 10   Locus: 10q11.21
Gene position52008370 - 51947000  Map Viewer
Gene orientationminus
Gene size61371 bp
Gene sequence
OMIM ID611202