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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMA3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5684
Official gene symbolPSMA3
Full nameproteasome (prosome, macropain) subunit, alpha type, 3
Aliases,HC8,MGC12306,MGC32631,PSC3,
Gene summaryThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q23
Gene position58711593 - 58738726  Map Viewer
Gene orientationplus
Gene size27134 bp
Gene sequence
OMIM ID176843