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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PAK6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID56924
Official gene symbolPAK6
Full namep21 protein (Cdc42/Rac)-activated kinase 6
Aliases,PAK5,
Gene summaryThis gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q14
Gene position40509629 - 40569688  Map Viewer
Gene orientationplus
Gene size60060 bp
Gene sequence
OMIM ID608110