Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC4A10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57282
Official gene symbolSLC4A10
Full namesolute carrier family 4, sodium bicarbonate transporter, member 10
Aliases,NBCn2,NCBE,
Gene summaryThis gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
LocationChromosome: 2   Locus: 2q23-q24
Gene position162480845 - 162841786  Map Viewer
Gene orientationplus
Gene size360942 bp
Gene sequence
OMIM ID605556