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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTGDS (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5730 Official gene symbol PTGDS Full name prostaglandin D2 synthase 21kDa (brain) Aliases ,L-PGDS,LPGDS,PDS,PGD2,PGDS,PGDS2, Gene summary The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq] Location Chromosome: 9   Locus: 9q34.2-q34.3 Gene position 139871956 - 139876194  Map Viewer Gene orientation plus Gene size 4239 bp Gene sequence >PTGDS:654959..659197:Length=4239 GCTCCTCCTGCACACCTCCCTCGCTCTCCCACACCACTGGCACCAGGCCCCGGACACCCG CTCTGCTGCAGGAGAATGGCTACTCATCACACACTGTGGATGGGACTGGCCCTGCTGGGG GTGCTGGGCGACCTGCAGGCAGCACCGGAGGCCCAGGTCTCCGTGCAGCCCAACTTCCAG CAGGACAAGGTGAGGGGCTTTCCTGCGTCATCCCCAAGGGCTACAGGACCCTGTCAGGGG AAGGGCACTTTCCGGCTGGGTCTTCCCCCTGGGAGGAGTGAGCGAAGTCCCGCAGTGCCG GGCAGTGCCGGCCAGGGACTGAGCGGGCGCGCAGGAAGGAGGCTGGGTAGCCGCCCGAGG AGGCTGCCCGCGAGAAGCCCTCCCTGGGCACCGCGTCCCGTCTCCCCTGATGGGCCACGC AGACACCGGGCCACACACGCGCCCACGCCAGCCAGACACGTCCACCCCTGTGGGCACGCG ACCCCCAGAGGACACACGAGCGCACGTTCCACACCTGGGTGCCAGGACACGGGCGGGTGG GGCACAGGGATGGCGACAAACACTCCGTGCGCGGTGGGGGTTGGGAGGGACGCGCACCGC ACAGACAGCCGGCGACGCGCGCTCTCGCCCGGGAGCTGCTCGGGGAAGCGCCGGAGCGCG GGTCCCCGCGCCGCGCGCCCCTCCCTGGCGTCGAGGAGAACCCCAGCGGTCCGCAGAGCT GAGCCGAAGACCCGCCCCGATCCCCGCCAGGAATGCGACGTCCTCTGCCGCCCGCTGTAT GGGCCAGGCGCTCAGCCAGGGCACAGAATCGGGACCGGGGGCGGAGGGGCCGAAGCTGGC TGGTGGGCGGCGTGCGAGGGTGAGGGACTGTCCTCGGGAGGGGCGTGGCCAGACGGGGGT GCTGGGTGTCAGGGGCGTGGCCAGCTTCTGGGGCTGAGGCGTGAGGGGCGGGGCCATCTC CGGGGGAGGGGGAAGTGGGGCGTGGTCATCTCCTGGGGCGGGGCGTGAGGGGCGGGGCCA CCTCCCGGGGCGGGGCGGGGGCCTGATGGGCGTGGTCAGCTCCTGGGGCGGGGACGTGAG GGGCGGGGTCAGCTCCTAGGGGGGCATGGGGCGTGAGGGGCGCGGTCAGTTCCCTGGTTG TGGACATGAAGGGCGGGGCCAGCTCTTGGGGCGGGGTCGTGAGGGGCGTGGTCAGCTCCT GGGGCGGGGATGTGAGGGGCGGGGTCATCTCCTGGGGCGGGGATGTGAGGGGCGTGGTCA GCTCCTGGGGCGGAGATGTGAGGGGCGGGGTCATCTCCTGGGGCGGGGATTGAGGGGCGG GGGTCAGTTCCTGGGGCGGGGCGTGAGGGGCGTGGCTGCTCGGGGGATTGGGCGTGGGGG CGGGGCCGGGTTGGAGACCGGAGGAGTAGACGGCAGAGGCGCCCCCGCAGGTAGGCGCAG GTGGGTCCGGAGGGTCCTGGCCGACGCGGGTGGGGGTCGCTCGCCGCAGTTCCTGGGGCG CTGGTTCAGCGCGGGCCTCGCCTCCAACTCGAGCTGGCTCCGGGAGAAGAAGGCGGCGTT GTCCATGTGCAAGTCTGTGGTGGCCCCTGCCACGGATGGTGGCCTCAACCTGACCTCCAC CTTCCTCAGGTGGGACAGCGGGCAGGTGGGTTTCTGGGACGGAGAGGTCCAGGGACACCC TCGGGCCTAACCCCTGACCCTGAGGTCACCCACCTACAGGAAAAACCAGTGTGAGACCCG AACCATGCTGCTGCAGCCCGCGGGGTCCCTCGGCTCCTACAGCTACCGGAGTCCCCGTGA GTGGGGCCTCCACCGGCCCCCTGGGCCCAGCCTGGGGGCGACACTTGCCGGGACGACTCT GGGCCAGCCCCCTGCCGCGGAGATCCATGGGGTGGGAGGTGATGGCTGCCCCACCAGCGT CAGAGGCAAAGGCCAGGCCTGGGCGTGACTACCCATGCACAAGTGTTAGGGACAGAGAGA CCCTTCCTCCAGGGGGTTGGATCCTCTCTGGAGCCCACCATTGTCTTGTCAGGCCCCTTC CCTGCCCTCTGGAGTTTTCCCCACATAAGCAGCCCCCCAAGGCCCCTCCATATGCCTCCT CCCAATTCTCCTCCCCAGGACCCAGGGGTTTCCTCACTCCCACCTGGGGAATGGCTCCCA CGGGGAAACCTCTTCACTTCCGGTTCTGGCAGCGACTTCTGCGGCTGCACCAGGAATCCT GGTTTTCTGAGCCTGGCTCCCCCAGATTCTGGTTTGGGGACAGGGTTCACAGGCTGTGCA GGCGAGAGCAGGGCACTGGCTGGAGAGCAGCCGGGTGGGGGAGCATCCCGGGCCAGCCGA GGGGCTGAGTGCCCCCAAAGCCCACAGGTGCACCCCTTCCCTGAAGCAGAGGTGAGGTTT GGGGGGCTGAGTCCCCGACAGGGTTGTCTCTTGGGTTCCCAGACTGGGGCAGCACCTACT CCGTGTCAGTGGTGGAGACCGACTACGACCAGTACGCGCTGCTGTACAGCCAGGGCAGCA AGGGCCCTGGCGAGGACTTCCGCATGGCCACCCTCTACAGTACGTGCCCCGTGGACGCCG CCCACACGCAGGCCTGACCAGAGGGGGCTCCCCAAGACCCAGGGCAGGGCACACAGCATC CCCCCCGCTGAGGCCAGCTCCGTCTCCACCCTGTCCCAGGCCGAACCCAGACCCCCAGGG CTGAGTTAAAGGAGAAATTCACCGCCTTCTGCAAGGCCCAGGGCTTCACAGAGGATACCA TTGTCTTCCTGCCCCAAACCGGTGAGGGGTCCTAATCTGATGGGGAGAGGATCAAGGTCA GATTAGAGGCAGGCAGGCAGTCTCCTGACTGGGGGAGGCAGAGGGGAGGAGGTGGCCCCG CCCTGCTCGAGGCCTGGGCCAGGGACAGAGGGGGTGAGTGTTCAAGTCAGAACCTCCCTC CCGCAGCCCCTTCATGAGGAGCCCCCTCCATGGGGGACATGGAGACCAGGCGCCCACTCT GTGCCAGGCCCCAGCAGCTCCCAGGATGTGGGGCTTCAGCCTGGTGGGGGGCATAGGGTA GAGGGTGCCCATGGGGGATACAGGGGAACCAACCATACTGGGCTCAGGCACAGCCTCCTA GGGGTGGACAGCCTGCTCTTGGCAGAGGTGGAGAAAGACCCTCTCTTTGTTTCCAGTGCC CAGGGAGAGGTGGGAGGTGATGGGGGATCTGTGCAGTTTGGGGGCTCAGTCAAGACGAGC TCTGCGTTACGGGAGGAACAGGAAGCCCAGTGGGAAAATTGGCCTAAGTCTGGGGTTCTG ACGACAGCCCCTGGCTTCTTTCTTGGCAGATAAGTGCATGACGGAACAATAGGTGAGCCA CTCCATTCATTCATTCATTCATTCATTCATTCATTCATTCAACACACATCCACCCAACCC ACTCTGCGATGGGATGGATCAGGGCCCCAGGACAGCCTGGTGCTGCAGACCCATCCTTCC CGATGGCTGCAGTCCAGGGCCGGGCGGGAGACACTGGGGCTGCCCACATTGATGGGTGCA CAGGTGTGAGGCTCAGAAGGAAAACCTGTCCCAGTGGCTGGAACAGGGCTGACTCCTGAA GGCTCATGGTTGGGGGGTGCAGGTGCGAGGCCCCAGGCAGACAAGGCCAAGGGGCTATAC CACAGGGACCACCTGGCAGCAAGGGTGTCTGGCTCCTGGGCTAGGAGGAAACCAGGGTGG GGGAGACAGGATGGGAGGGAACAGGGGATGGAAGGGGAGGGCCAAGGACGCTACATGGAT GCCGTGGGACAGCTCGGAGAGCAGGCTCAGGGCGGATTCACCCACCACCCCCAGGAGGGA GGCCTAGGCTGGAGCTGGAGTCTGTGGACCCTGGGGCTGGGAAGGGTGGAGTCTGTAGAC CCTGGGGCAGCGGGGATCCAAGCCCCAGGGATGGATCTTGCTCTCTCAGCGGGGCTCAGT GGGGCTGGGGGCAGAGAAAAGTCCCCGTAGCCCGCACCTGCTCCATCGACTGGAGTGGAG GTGGGCTGGGGTAGACTGCAGTCCTCCATCCTAGCCTTTCGGTCACACCCCTCAGGACTC CCCAGGGCTGAAGCTGGGATCCCGGCCAGCCAGGTGACCCCCACGCTCTGGATGTCTCTG CTCTGTTCCTTCCCCGAGCCCCTGCCCCGGCTCCCCGCCAAAGCAACCCTGCCCACTCAG GCTTCATCCTGCACAATAAACTCCGGAAGCAAGTCAGTA OMIM ID 176803