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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAVS (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 57506 Official gene symbol MAVS Full name mitochondrial antiviral signaling protein Aliases ,CARDIF,DKFZp547C224,DKFZp666M015,FLJ27482,FLJ35386,FLJ38051,FLJ41962,IPS-1,IPS1,KIAA1271,MGC3260,VISA, Gene summary Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005 [PubMed 16239922]).[supplied by OMIM] Location Chromosome: 20   Locus: 20p13 Gene position 3827449 - 3856762  Map Viewer Gene orientation plus Gene size 29314 bp Gene sequence >MAVS:3767449..3796762:Length=29314 TGGCCAATGGCCGCGCGCTCTGCCCGCCCCGCCTCCTCGCTGCGGGAAGGGTCCTGGGCC CCGGGCGGCGGTCGCCAGGTCTCAGGGCCGGGGGTACCCGAGGTAAGATCGCTTCCCGGG CGTTGGGTCCTTTCGGCTCAGCACGCACGGACGCCTTTAGGGAAGGTGGCTGCAGCGGCA GGACGGAGTCCGCCGGGACGCCCTGGGTCTGGGGTGCGCGGGGGGCCCAGGAGGGGACAG GACGCGCGGGGATCCGGAAGAGCGGGCCCTGTCGCAAGAGTTTCGGGAACACTGAGGGCT CCAGGCGCCGCATCCAGCATCCGGGGAAAAGGGGGTAGGTGGCGCTGGGCGTCTGCTCAG GCTGGGGGAAAGGTAGGGCCAGAAGGGGACGGGCAGCGGCCGCTGACCTCCTCCTGCCGC CCGCGGGCCCAGGGTGACGCTAAGGTGGGGCCGAGCCTCGACCGGGTGCGCCTAGAGGTC GAGTGCTGCCGCCCTCCGCTGGGTCTGGACAGTTCTCGGCGGCGACACCAGCTCAAAACG GCCTCCCCGCCCTCCGCGGACCTGGGTCGCGCCCAGGAATCCGATCCAAGGCTGTGAGGC CTGTCCCTTTGGGAAGGGTGGGTGTTTATTTCCGGGATGCACTCAGAGCCTCTGGACAGT CAGGTCGGAAACTTTGCTGTATTGGGAACACTCTGTCACCTACTTCCTTCTCAGTTGGGA AGGAAGTGCCAAGAAAACATGAAACAAACCAAAAACACGAAAAAGGGATTCTCTGTATGG AAGCCGTGAAGCCTCAAAAATATCTAGGAGGACAGCCAGCGACCTGGGACCTGTGGCAGC CATGTGAAAGCAGGGTTAATGTCTGGACTAAATGTTGCTTCCACCTAAGTGCACCCTCAG CCTCCCTCCCGCCAAGTGACCTTGGGTCCTCTTTGGGCTTGAAGGCAGGTGGCTGTGTGG GTCTCGCTGCAGGGGTCTCTGTGCCCTGCAAGGTGTATGACCAGTTGCAGTGAGGCAGCA GGTTTTGGGTTCAAATCCTGTGCTAGCCTCTGGCCAGCTGTGCACCTTGGCAACACTTTC CCTGTCACGGGATTGGGGAAGGATTAACTGAAAGAACCTTAGGATGTGCCTGTCTACAAT GGGCCCTCCATAAATGTGAACAAATGTGGGCTTCCTTTCCTTTTGTTTGGGCCACATCAT CCCTTCCCCTCCATCTGTGGCTGAAGCTGGAATGCAGAAGAGTGCCTCATCTGACTGCCT TCTGGTACCTGGCTGATGCCATGAGAAAGGAAGGAGAAAGGGGTCTTTTTTTTTTTGAAA TGGAGTCTCACTCTCTTGCCCAGGCTGGAGCGCAGTGGTCCAATCTTGGCTCACTGCAAC CTCTGCCTCCTGGGTCTAGAGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAG GTGTGTGCCACCATGCCTGGCTAATTTTTGCATTTTTAGTAGAGACGGGGTTTCACCATG TTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAA GTGCTGGGATTCCAGGCGTGAGCCACCGCGCCCGGCCGAGAAAGGGATCTATTAACTCCC ATAGAGTTGTTCTTTGCTAATTTCTTGAAGGCTCAGAGGACCCCCGCCTCACCTTCCTGA TTCTCCTGACCTGTCATTAGTACTTGCCCCACGAGGAATGTAGCAGGGCCTGCTGGCTGG CAAAGCAACTCATGCATGTGAGGCTCTGAGGCCAGTGACAGGACTGCTTCCCCTGTGAGG AAGGTCTGGTGGCCCAACAGCTTTTAGGTGCTGTCTGCTCTACAGCACTGCCTCCTGAGA GAGGTCTCATGCCTGCCTGATGCCCACTTGGTCCTCTCCTGCCTCCTTCCCTCCCTGACA ACCCACTTGGAATCCAATAGCATCTCAAACTTCACTTGTTCCGAACTGAGTTCTGGAGTC CCTTCTGAGCCACTGCTCCTCCCCTGGCTTCTCTGGCCTGGTAAAAGGGCACCTTCCATC CACCCAGTGCCCAAGGAGTCATGCTTCTTTTCTCTCCCTTATCTCCTACACCCTCAAAAC ACCAGGAATCTGGCTGCCTCCTGCCATCTCTGTGGTTCCCATCCTGACCATAGTCATCCT GTCTCCTGGGCTGTGGCCTCCTTACTGGTCTCCCAGTTTTCATCCTGGCCCCTCCAAAGT CCTCACAACCACCAGAGAAGTCTTTAATGTAAATCAGATCCTCTTCTTTCCCTGCCGGAA CCTTCCAGTGGTTCCCTGTTTCACTCCAACTAAAACCCAGAGTCCTTTCCTACAGCACTC TACATGAGTGGCCCCTGCCACCTCCTTGACCTTGACAATCTCTGCCCCTTTCCCTAGCTT GCTTGCTTTTTTTTTTTTTTTTCCTATGATGGAGTTTTGATCTTGTCACCCAGGCTGGAG TGCAATGGGATGATTTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCCCACCACCATGCTAATTTTTGTATT TTTAGTAGAGAAAGGGTTTCACCATGTTGGCGAGGCTGGTCTCAACCTCCTGAGCTCAGG TGATCCACCCGCCTAGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGTCACGCAGCCAG CCATCCCTAGCTTTCTTGACCTAGACCACACTGACCTGCTTTCTATTCTTCAAACATGCC AAGCTCATTCTTGTTTTAGGACTTTTGCATTTACCATGCTCTCTGCCTAAAACACCAATC TTCTCAGAGCCTGAGAACAGCTCAGCTGTGTTCTGCACGCTAGTTCAGAAAGGCTTCTTT GACCCCCTAGTTCAAGTAGCATGCCTGTCTCCAGGGGCTCTGTCTCATTACCTGCTTTAC TTTCTTTAGAGCCTTTATTGCTATCTGGAACTCTTATTTGGGTATTAATTTACTGATCTG TTATTTGTCCCACCCCATTAGAATATAAATTGGATGTGGCATAGACCTTGTCTCTTTTAT TCCCTGCAGCACTCCCTGATGGGGGCGGCAGAAAAGTAACGAGCAAATACATCTATAACT GCAAATTGTGGTAACTCCTACATAAACAACTGGCAGCAATTGCTTATATTTGAGGCACTT AAAAATTTTTAAGCTGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAG GCCGAGGCGGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAA CCTGTCTCTACTAAAAATACAAAAAATTAGCCGAGCGTGGTAGCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGGCGGAGCTTGCAGTG AGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGAAGGAGCGAGACTGTCTCAAAAAAA AAAAAAAAAAAAAAAAAAGAAATTTTTTTAAGCTGCTGGGCGCGGTGGCTCACGCCTGTA AATCTCAGCACTTTGGGAGGCCGAGGTGAGCGGATCACCTGAGGTCGGGAGTTCGAGACC GGAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCGGGGCGTGGTGGCTCA TGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGC AGAGGTTGCAGTGAGCCGAGATCGCGCCATTGTACTCCAGCCTGGGCAAAAAGAGTGAAC TCCATTTCAAAAAAAAAAAAAAAGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCAC TTTGGGAGGCCGAGGCAGGCGGATCACGAGTTCAGGAGATTGAGACCATCCTGGCTAACA CGGTGAAACCCTATCTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCGGGCGCC TGTGGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCAGGAGGTGGAG CTTGCAGTGAGCCGAGATTGCACCACAGCACTCCAGCTTTGGTGACAGAGCGAAACTCCG TCTCAAAAAAAAAAAAAAAAAAAATTTAAGCTTAGAGGCCGGCCACAGTGGCTCAGCACT GTGCAGGCCAAGGCAAGAGGATCACTTGAGGTCAAGAGTTCGAGACCAGCCTGGCCAACA TGGTGAAACCCTGTCTCTACTAAAAAATACAAAAATTGGCCAGGCGCGTTGGCTGGCGCC TGTAATCCTAGCAACTTGGGAGACCAAGGCAGGCAGATCACCTGGGGTCAGGAGTTCAGG ACCGGCCTGGCCAACATTAAAACATATAAAACCCCGTCTCTACTAAAAATATAAAAATTA TCCAGGCATGGTGGCGTGTACCCGTAATCCCAGCTACTCGGGAGGCTGAGGTAGGAGAAT TGCTTAAACCCGAGAAGCAGAGGTTGCAGTGAACCGAGATTACGCCACTGCACTCCAGCC TGGGCAACAGAGCGAGACTCTTTCTCAAAAACAACAACAACAACAAACAAACAAATTAGC CAGGCATGATGGTGGGCACGTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTG CTTGAATGTGGGAGATGGAGGCTGCAGTGAGCCGAGATCACACCACTGCACTCCAGCCTG GGCGACAGGGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAGTTTATAAGGCTGAAT TACCGTACTGTCAAAACAAGCTGCTATCTGAGCCGTTTTAAGGGTGAGGAAGTCTGGAAA CTGATAACTTGCCCAGGACACACAGTGAGTTCAAGGCATGGAACTCAGTCTCCTATCTTA AGAATGTATGTGGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCC AAGGCAGGCAGATCATCTGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGAGAAAC CCTGTCTCTACTAAAAATACAAAATTAACCAGGTGTGGTGGTGCATGTCTGTAATTCCAG CTACTCAGGAGGCTGAGGCAGAAGAATCACTTGAACCCGGAAGGCAGAGGTTGCGATGAG CCGAGATTGTGCCATTGTACTCCAGCCTGGGCAACAAGAGTCTGGAACTCTGTCTCAAAA AAGAAAAAAAGAATGTATGTGTAGCAGGCTTTTTTTTTTTTTTTTTCCCCCGAGACGGAA TCTGGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAAGCTCCG CCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCAC CCGCCAGTACGCCGGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTA GCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCT GGGATTACAGGCGTGAGCCACCGTGCCCGGCCTATGTGTAGCAGGCTTTAATGGTGGGCC TGCAGCCATGTCATGGAAAGAAGCTGACCTGAAGATCTCAGTTCTTTCTTCTTCTACTAA CTAGCAAGCATACCTCAGTTTCTTCTTTAAAGCGGGATGATCCGATTATTATCATGTTGG GGTTCACTTTTTATTTTTTCAGTGTGTCCCAAAGCAGCAGCACGTTTAGGTATAGCCCTC TTGCTATCAGCTTGAGGGCCTTAGAGCCAGGAAGGGAGCCAGGACATTTATAGGCACAGA AACTAGGGTCACATACAGATCCCCCCACCGCATGTGCTAGGGGTACATGCAGACCTTCCC AGTGCTGACCAACCTGCAGAGAAGAAATGGGCCCTAGGTATTCTGGATCTGATTCTTTTT GGTCTTCAATTATTTTTATTTTTATTTTTTTAGAGACAGGGTCTCGCTGTGTTGCCCAGG CTGGCCTCGAACAGCTGGGCTCAAGCGATCCTCCTGCCCTAGCTTCTTGAGTAGCTGGTG GTCATCAATTCATTTTTAGCAAATTCTGCAGAATTTTTTTTTTTTTTTTTTTTTTTGAGA CGGAGTCTCACTCTGCCGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTACAAC CTCCGCCTCTTGGGTTCAAGCAATTCTCTGTCTCAGCTTCCTGAATAGCTGGGACTGCAG GCGCCCGCCACCATGCTTGGCTAATTTTTTTGTATTTTCAGTAGAGACGGGGTTTCACCA TCTTGGCCAAGTTGGTATTGAACTCCTGACCTCGTGATCCATCCGCCTCGGCCTCCCAAC GTGCTGGGGTTACAGGCGTGAGCCACCGCGCCCGGGTTCTGCAGGAATTTTGGAGAGACT CAGGCAGTAATAAAATAGGATGTTTACAGAAATTAAAGATGGCGGCCGGGCGCGGTGGCT CACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGCATCACGAGGTCAGTAAAT CGAGACCATCCTGGCTAACCCCGTGAAACCCCGTCTCTACTAAAATACAAAAAAATTAGC CGGGCGTGGTGGCGGGCGCCTGTCGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGG CGTGAACCCGAGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCACCGCACTCCAGCCTG GGCGACAGAGAAAGACTCCGTCTCAAAAAAAAAAAAAAGAAATTAAAGGTGGCTGGACAC ATTGGCTGGTGCTTGTCATCCGAGCTACTTGACAGGCGGAGGCAGGGGGATCGCTTGAGG CCAGGCGTTTGAGACCAGCCTGGGCAGCATCATGAGACCCTGTCTCTAGAAAAAATAAAA AAATTAGCTGGGCATAGTGGCGCAGGTTTGTAGTTCCAGCTACCGGGGATGCTGAGGCGG GAGGATTGCTTGAGCCCACGAGTTCGAGGCTGCAGTGAACTATTATTGCACCACTGCACC CAACTTGGGTGACAGAGACCCCATCTGTTTGTTTGTTTGTTTTTGAGACAGAGTTTCGCT CTTGTTGCCCAGGCTGGAGTGCAATGGTGCAATCTTGGCTCACCGCAACCTCTGCCCCCA GGTTCAAGCAATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCATGCGCCAC CATGCCCAGCTATTTTTTTTTTTTTTTTGTATTTTTAGTAGAGACGGGATTTTCTCCATG TTGGTCAGTCTGGTCTCCAACTCCCGACCTCAGTTAATCCCCCAAATTGGCCTCCCAAAG TGCTGGGATTATAGGCGTGAACCACTGTGCCCAGCCCGAGACCCCATCTCTTAAAAACAA AATAAAACAAAACAAAAACGGCCAGGTGTGGTGGCTCACACCTGTAATCCCCAAACTTGG GAGGCCGAGGCGGGTGGACCACTTGAGGTCAGGAGTCTGTGACCAGCTTGCCAACATGGT GAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCGCACCTGTAA TCCCAGCTACTCAGAAGGGAGGCTGAGGCAAGAGACTCAATTGAACCCAGGAGGCGGAGG TTGCAGTGAGCCGAGATTGCCCCACTGCACTCCAGCCTGGGTGACAAAGTGAGACTCGCT CTCAAAAAAAAAAAAAAGAAGAAATTAAAGATGAAAGAAAACAAACATTCCAAAAAGTTG AGAAAGAATTGCCTTTTGTCCAGCCCCACTCCCAACCCCCCAACCCTGTTGTAATGTGTG ATCTGTTTTCTTCCAGTCTCGTTTCCTCTCAGTCCATCCACCCTTCATGGGGCCAGAGCC CTCTCTCCAGAATCTGAGCAGCAATGCCGTTTGCTGAAGACAAGACCTATAAGTATATCT GCCGCAATTTCAGCAATTTTTGCAATGTGGATGTTGTAGAGATTCTGCCTTACCTGCCCT GCCTCACAGCAAGAGACCAGGTGAGCAAGGGAAGTGACAGCCCGACACTGGCCTGGGGGC AGGGCTGTGGAATTCAAAGCTCAGCCCCATCCTAGTTCCTCACCCAAGCCTGGGCTGGCT CCTTCCTTCTTCCTCTTGCTGTGTCTTGCTCCTTGTCCTTGCTGCTTTTCTTTTTTTTTT TTTTTTTTGAGATTGAGTCTCGTTCTGTCGCCAGGCTGGAGTGCAGTGGCACGATCTTGG CTCATTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAG CTGGGATTACAGGTGCGTGCCACCACGCCCAGCTAATTTTTTTGTTTTTAATAGAGACGG GGTTTCACCATGTTGGCCAGGATGGTCTTGATCTCTTGACCTTGTGATCCGCCTGCCTCG GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCTTGCTGCTTTTCTAACT TTTGGATGGAGTGTGGCTCAGGGTGGCGTTGCTGACTTCGCCGAGCTCCCCCTTGTGTTG CTTTTGTGCACTGCTCAAAAATATGGCGCTGGCTCTCTGAGATTTCCTGGCTCTGGTCCA CTTGCCCACTTTTTTTGGAACCTCCTATTTCCTTCATCTCTCTTGCCCTTCCTTGTCCTG CTCAGTTTTGATTCCATTCTCCTTGTCATGGGGCCCTGTCCTGGCACGGAGCTGGGACTC AGGTTTGAGAGCTGGCAGGATCAGGGTCGCTCTAGCCCCAACAGAACTTGCTGCAGGCCC CTGGCACTCACTAGCTGGTGAAACGGGCACAACCCCTCCCCGTTGTAGCTGCTGTTCTCA GATTGGACCCCTGTGCTCCAGAGGGTACCTGTTGGCTCTTTTGGGGCCTCCTGTCCTCAG ATTTCTCAGGAGCCCCATTGTTGTCTCCGCTGTCCTCCCACACAGATCGCATTAGTATGC AGGTCTGTTTGGAGTTTGCTCCTCCCTCTTGTATTTTGGGGTTTATAGGGATATCTTGTT TTATAGTAAATATTTTCTGTGGGTTTTCTTTATTTTCTTTAAAAAATTTTTTTTTGAGAC GGAGTCTCGCTGTGTTGCCCAGGCTGCAGTGCAATGGCATGATCTCAGCTCACTGCAACC TCTGCCTCCTGGGTTCAAGTGATTCTCGCGCCTCAGCCTCCTGAGTAGCTGGGGTTACAG GCGCATGCCACCACACCTGGCTGATTTTGTATTTGTAGTAGAGATGGAGTTTCACCATGT TGGCCAGGCTGGTCTTTATTTTTATTTTTGAGACAGAGTCTTGCTCTGTCACTCAGGCTG GAGTGCAGTGGCACGATTTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTCGCCCAGGC TGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAAGCTCTGCCTCCTGGGTTCACGCCATT CTCCTGCCTCAGCCTCTTGAGTAGATGGGACTACAGGCGCCTGCCACCATGCCCGGCTAA TTTTTTGTATTTTTAATAGAGACGGGGTTTCACTGTGTTAGCCAGGATTGTCTCGATCTC CTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCA CTGCGCCCAGCATTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTCTTCCAGG CTGGAGTTGCAGTGGTGCCATCTTGGGTCAACCTCTGCCTCCTGGGTTCAAGCAATTCTC CTGCTTCAGCCTCCTGAGTAGCTGGGATTACAGGTATATGCTACCACACCCGGCTAATTT TTGTGTTTTTAGTAGAGACGGACTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGA CCTTGTGATCCTCGGCCTTCCAAAGTGCTGGGATTACGGGTGTGAGCTACCGCACCTGGC TATTTTCCTTTTTCTAAAAATCTAGCTCCTGCAGGATTCTGTGGGTTTTTGTTTCTGCTG TCTGGTTGCTTGTTTTTATGTGAGAATTCAGGTAGACATAAAAACTCTAGGGCTGGGCAC GGTGGCTCACGCCTGTAATCCCAGCGCTTTGGGAGGCCAAGGCGGGTGGATCACCTGAGG TCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCATGTCTCTACTAAAAATACAA AAAAATTAGCCGGGTGTGGTGGTGGGCTCCTGTAATCCCAGCTACTCGGGAGGCTGAGGC AGGAGAATCGCTTGAACTCAGGAGGCAGAGGTTGCAGTAAGCTGATATCACGGCACTGCA CTCCAGCCTGGGCGACGGAGTGGGACTCCGTCTGAAAAAAAAAAAAAAAAAAGAAACAAA AAAACTCTGCAGCCACTGTCATCTGCCCACAATCTCCCCAGCATTCTCAGCTTCCTTGTT TGTTATTGTCGGCCCCCTCTCTTTCCGTCTTTTGCCCCTTTCATCATACTTTTGCTATCT ACCTTTTCCTTCTCTCCTAATCCAAACCTTTCTTTTTGCCCTGGGGGCCATATTAATCCA AGGCTTTTGTATCAGATTAACTGGGTTTGGATTCCTGCCCCACTGTTTTAGGATCTTTGC TACAGTACTTTGCTTCTGCTAAGCCTCAGTTTCCTCATTAGTAAAGTGGAGATAATAATG GCATTAAATAAAGATGATACATGCAAAGCCCTTAATGGAGAGCCCAGGACATAGTTAATT GCCAGTTTCCGGCAGCTGCCTTTATTGATGTGGCTGCTAATTGCTCTTCCTCACTCCATA CCTGGCCCTGTCCTGGGCTCCGATCCAGTTTCACGTGGCTGCCTTGCCCTTGTGGCTTTC TTGGCACCCCTCCCCCCGCTGTGGCTTCATTCTGGGTGGGGAAGTGGCAGGGGCCACCTG GCTTGAGCAGGACAGTGGCATTGTGTCTTCCAGGATCGACTGCGGGCCACCTGCACACTC TCAGGGAACCGGGACACCCTCTGGCATCTCTTCAATACCCTTCAGCGGCGGCCCGGCTGG GTGGAGTACTTCATTGCGGCACTGAGGGGCTGTGAGCTAGTTGATCTCGCGGACGAAGTG GCCTCTGTCTACCAGAGCTACCAGCCTCGTGAGCGTCCTGCCCTTGCCCTCCTGGACCCC CAGCCTGCTCCCTGGCCTCCGCTCTCCTTTTCTCTCTCCCTGTACTTCCTGCCTTTCTCT GTCATCCTCTTTCTTGTCACTGTGAAGCGATGAATAAACCTGGGTGTAGATCCAGGCTGA GCCACTTACCAGCTGTGTCCCTTTGGCCAAGTCCCTTAATTTCCCTGAGCCTCAGGCCTC TCTTCTGTAAAATGAAGCTCATGGCAGCATCTGCCGCGGGGAGCTGCAGTGGGTGATACT GCGGGACGATGCGTGTTGAGTATTGAGCTGGGCTGGGCACTTCCTGTATGCCCAGCACAT GGAGTCTCCCCTAACTTTCACGGCTGTAGCATTCGCCTCCCACCCTTCCTCATTTCTTCT CCCCCACCTACTCATTCACCCTCCCTCTCTCCTCCTTCTCTTCCCCTCCCCTGGTTTACC CTGAGAGCCTTCGACGCCCTCTATCAGCTGCCCAGTTATTCTTTAAGTCCCTCTCAGTGT CCCTGCCACTCTGAGTGCTCGGAGGCGATTTGATGAGATTGAGTTTGATCCTGAGTGAGA TCAAGACATGGGAGGAGGCTGGGCGCGGTGTTTCACACCTGTAATCCCAGCACTTTGGGA GGCCGAGGCAGGCGGATCATGAGGTCAGGAGATGGAGACCACCCTGGCTAAAACAGTGAA ACCCCGTCTCTACTAAAAATACAGAAAATTAGCCGGGCATGTTGTCCCAGCTACTCAGGA GGCCGAGGCAGGAGAATCACTTGAACCAGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGC GCCACTGCACTCCAGCCTGGGCGACAGAGTGGGATTCCATCTCAAAAAAAAAAAAAAAAA GACATGGGAAAAAAAATCAAGCCAGCCCTATTTATATTTCAAACTAGAGGTAACCCCCGA GACCCTGGTCACATTTATAGCTGTGGGACATCCATGTTTTTCTTTTCTTTCTCTCTCTTT TTTTTTTTTCCTTTTAGAGACAGAGTCTTGCTGCGCCACCCAGGCTGCAGTGCAGTGGTG CAATCATAGCTCACTGCAGCCTTGACCTCCTGGACTCAAGTGATCCTTCTACCTCAGCCT CCAGAGTAGCTGGGACTACAGGCATGGACAACTACACCTGGCTAATTTTTAAATTTTTTG TAGAGATGACATCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTGAAGCGATC GGCCTCCCAGAGTGCTGGGATCATAGGTGTGAGCCACCGCGTCTGGCTCTCATGCTTGCT TTTCTCTCCTTTTTCCCTTCCTTGCTTTTCCTCCCTCCCTCCCTCCCTTCCTCTCTTCCT TCCTTTTTTTCCTTCCTTCTTTTTAAATATGTCTCTTCATGTGTGGAGATTAATAGTGAT CCCTGGCTGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGG CGGATCACAAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGTGAAACCCTGTCTGTA CCAAAAATACAAAAAAATTAGCTGCGCATGGTGGTGCAAGCCTGTAATCCCAGCTACTTG GGAGGCTGAGGCAGGAGAATTGCTTGAACCGGGGAGGTGGAGGTTGCAGTGAGCCGAGAT TGCGCCACTGCACTCCAGCCTGGATGACAGAGTGAGACTCCGTCTCCAAAAAAAAAAAAC CCAAAAATAGTGATCCCCTGAATACAATGGCTGTGGTAGGGCCTGATGAGGGGTGGGGGC AAAGGGGAGGGGCTCAGGTGGCAGCATCAGGGCAGGGGTCAGTGAGCAATGATAGTCATG TGGAGGAGAAAGCCACTGGGTCCTAGGATGCCTGGGGACAGAGAAGAGTGACTGCTGACA CGGCGTGGGTGACTAGAGACCCACGAGGCCCCCCCATACTCCCCTTCCTCCCTTGCTACC TTGTCCTCCATCTGCTCTCACCCTCCCACTCCTGCCCCCTTGCCAAGTGATGCTTGTCAC TCCTTTTTTTTTTGAAATGGAGTTTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCA TCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCC GAGTAGCTGGGACTACAGGCGCCTGCAACCATGCCCGGCTAACTTTTTGTATTTTTTAGT AGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCAC CCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCCAGCCCTGCT TGTCACTCTTGAGGAGTGGGCCCACATCAGAACAGCTTTTGGACCTATGGGTGGGGCGGG GGGTGTACCCAAGAGCACCCAAGCCTCTTTAATCATGAGGAGAACCCCCAATTCCTTTTT TTTTGAGACAGAGTCTTGCTCAGTCGCCCAGGCTGGAGTGCAGTGGCATGACTTCGGCTC ACCACAACCTCTGCCTCCCGGGTTCAAGTGGTTCTCCTTCCTCAGCCTCCCTATAGTCCC TGATTCCTTCTATTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTTGTTGCCCAGGC TGGAGTGCAATGGTGCAATCTCAGGTCATGGCAACCTTCACTTCCCAGGTTCAAGCAATT CTCCTGCCTCAGCCTCTCGAGTAGCTGGGATTACAGGCATGCGCCTCCACGCCTGGCTAA TTTTGTTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCA CGACCTCAGGTGATCCACCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCC ACCACGTCTGGCTTCTTTTTCTTTTTTTCCCCCGAGACGGAGTCTTGCTCTGTTGCCCAG GCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGTCTCCCAGGTTCAAGCAA TTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCTTGCCAGCACGCCTGGCT AATTTTTGTATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACT CCTGACCTCCTAATCCACCTGCCTTGGCCTCCCCAAATCCTGGGATTACAGGCATGAGCC ATCGTGCCCAGCCCCTGATTCCTTCTTTTTTTTTCTTTCTTTTTTTTTTTAGACGGAGTC TCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTTACTGCAAGCTCCGCC TCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGGGCCC GCCACCATGCCCGGCTAATAATAATGTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGT TAGCCAGGGTGGTCTCGATCTGACCTCGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTG AGATTACAGGCATGAGCCACTGTGCCCAGCCCTGATTCCTTCTTGATATCACTACATCTT TGTCCTCTAGGGACCTCGGACCGTCCCCCAGACCCACTGGAGCCACCGTCACTTCCTGCT GAGAGGCCAGGGCCCCCCACACCTGCTGCGGCCCACAGCATCCCCTACAACAGCTGCAGA GAGAAGGAGCCAAGTTACCCCATGCCTGTCCAGGAGACCCAGGCGCCAGAGTCCCCAGGA GAGGTCTGTCCTCATAGTCTACCTTGAGCCACCACTTTTGTGTTCCTATCTGCCCACTTC TGCCCATTGAGCCTTCCAGAAACCCTCTCCCGTCCCCTATAAATCACGCCTAATCTCTGC TCAGAACCCTAGGGCTTCCTCAGTGGGGATCTGCCCCAGACCAGCTTCCAGGCTGCTGAC CAGGTCTTCACCCTGTGGCAGCCCTAATCCTCTGTCAGCAACCAGCTGGGAGACCACAGT TTTGTGTGTGTGTGTGTGTGTGTGTGTGACAGTGTCTCATTCTGTCACCCAGGCTGGAGT GCAGTGGAGTGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAGGTCATTCTCCTG CCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCCACCACCACGCCCAGCTAATTTTTG TATTTTTAGTAGAGATGGGGTTTTGCCGTGTCAGCCAGGCTGGTCTCGAACTCCTGACCT CAGGTGATCTGCCCACCTTTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCA CCTGGCAATGCTGTGTGTTTTCTGTGAGGTAGACGTAAGGACACCTGTGGACAGAGGGTC TGGGAATTACCAGAACCCAGGCAAGGGCTCCCCTGGCTCCTGTGCTCCATGGTGTGGGCT GAGGCCTATAGGAGATGCCCCAAGAGCACAAGCTGCCCTTTGTGAGCTCTTGGGAGAGGC AACTGCCTTATTCATATTTTCCCTCATTGCAGAATTCAGAGCAAGCCCTGCAGACGCTCA GCCCCAGAGCCATCCCAAGGAATCCAGATGGTGGCCCCCTGGAGTCCTCCTCTGACCTGG CAGCCCTCAGCCCTCTGACCTCCAGCGGGCATCAGGAGCAGGACACAGAACTGGGCAGTA CCCACACAGCAGGTATGCATGGAATCTGGAATTATAGGGTCCTTCTGATCTCTCAAGTGA GGGTAAGAATTAGAGTTGCCCCATCTGGCTTCCTTGAACAGGAGACAAGGTGGGAATAAA GGGAGTTCAACCCAGGAAGCAAACCAGTTCCTTAGTGGGTGTATCAGTTAGCATTTGCTG TGTAACAAATAGTCCACTCCAGTTTTCCAAATTTTTTTTTTAGTAGCTTAAAATACAGCC ATTTATTTAGCATATGATCCTGTGGGTCAGGCATTTGGGCTACCTACATGGGCATTTCTT CTGGTCTTGGCTGAATTTCCTCTCAAGTACTCACCGGTATATACATAAGTTCTGCCTCTG GCTGTTTGCTGAGCACCTTGGTTCTCTTCTATGTAGTCTCTCATCCTCCAGCACACAAAC CCATCATGGCAGCTGGGCAGAGTTCTCAGAGAGGGCTCAAAACTGGCACAGTGTCCCCTG TGCTCCATTCTGTGGGCAAAAGCAAGTTATAAGGCCAGCCTAGATTCAAGGAGTAGGGAA ATAGACTCCCTCCCTAGACGGGAGGACTGACAGGCACAGTGCAGTGGGGCTGGGTGGAGA TGAGCGAGATAAGTAGGGCCATTTTTGCGCTCTGCCAAAGGGACTGTAGGGAACAGCCAG GGCCTATAGGGCAGTGGGAGAGGGACAGTGAAGGGCTGCATCAGCTGTTGGCAGGGGAAC CTTTAGGCACTGTCTTACCGCAGAGATCTCCAGTTCCCAGTGAATCATGAAAACTTCTCA GTCCCCAGAGGAAGTAAGGTCTTCATCATCCAGTGGCCTGGACTCAACTCCAGATGTCAG TGCTCCCCCTCAGAAATATATAGTTGTCCATCTGGACCTCTCAGGCCAGCATGTCTCTTT CCTACTTCCCAAACTATTCCACATGACGCTGGTGCCCAGTCAGCCCTCAGTGCCCTGGGA CAGCCACAAGACACATGAGCAGTTAGAGGCTGGGAGACGTCATCTTAGTACTTTTGTCAT CCCCAAACTGCTCCAAGCACCTGTCTGCTTTGCAGTGTCACCTGGCCACGGGATGCCTTT CAGGAGTTGCTGTAGACCACAGAGGCAGAGGGCGCTTAGGTTTCAGTACGTTTGTAGACA CAGGTCCCATGAGATTCTGTGGTATTAGATTGTGGTGGGGGAGCTGTACATCAGAATCAC CCTGACTTTTGCCAGCTGTGGGGCTTGGCATGTGCATTCCGAGTTCCGTGGAGAGTCCTG CTGCAACTGCCTTTACAGACCATCACCACCTGCTATCCTCTGCTTCCCCCACCCAGGTCA GGCAGCCTCCCAGGGGTGGCTTTGTCCTTGTCCCCTCTCTTCCCAAGCCTCCGGGATGGC CAGGCCTCTCGGCTGGTGTGAGCTGTTCTGCATGAGCCATCCTGCCACCCCTTGCCCTGA TCCATGGCTGCTCCCACTCATGGTGGTAGGAGAGGGACAGCAGTGGGGGAAGTGTCCAGG ATTGCATGAGGCTAAGGTCAAAGTAGAAAAGGTAGACACAGGAGAGGGGAGGTTTCCCAG GTGGGAGAGGAAAAAGCGGAGAGAATAATTAATAATGGTCTTCAGGCTCCTAGGTACCAT TTCACTGTGTGCCAGGACAGACCTGGGGCTACAGGTCAAGGACTGAGGGCAGCTGTTGGG CTTTCAGGCCAGGAAGCAGTGACCAAAGGGACTGTGGCATCTCCTCCAAGGGCAGGAGAT TTGGAGGCCTAGACACAGTAGGGACCATGAGATCTGGGCCAGAGGGACCCTTCTCCAGGC CTCAAGGTAATGGTCTTTGGGTCTGTGTTTCCACTTGTGTTTTTCCACCGGCAGGTGCGA CCTCCAGCCTCACACCATCCCGTGGGCCTGTGTCTCCATCTGTCTCCTTCCAGCCCCTGG CCCGTTCCACCCCCAGGGCAAGCCGCTTGCCTGGACCCACAGGGTCAGTTGTATCTACTG GCACCTCCTTCTCCTCCTCATCCCCTGGCTTGGCCTCTGCAGGGGCTGCAGAGGGTAAAC AGGGTGCAGAGAGTGACCAGGCCGAGCCTATCATCTGCTCCAGTGGGGCAGAGGCACCTG CCAACTCTCTGCCCTCCAAAGTGCCTACCACCTTGATGCCTGTGAACACAGTGGCCCTGA AAGTGCCTGCCAACCCAGCATCTGTCAGCACAGTGCCCTCCAAGTTGCCAACTAGCTCAA AGCCCCCTGGTGCAGTGCCTTCTAATGCGCTCACCAATCCAGCACCATCCAAATTGCCCA TCAACTCAACCCGTGCTGGCATGGTGCCATCCAAAGTGCCTACTAGCATGGTGCTCACCA AGGTGTCTGCCAGCACAGTCCCCACTGACGGGAGCAGCAGAAATGAGGTGAGTCCTCGCC CTTCCTGGCAGGGATCCTGGCCCCTTCCCCCGGGACAGCTTGCCCACCTGGCCCTGGCCT TGGCCCCTTCCCAGTCTGCATTCTGTGTCCAGCCTGTGCTGCTCTGTGGCCTCTCCTTGA GGGCATACAGACAGTTGAGAACCAGCCTCATGCAGGCCCCACACCATGTTCTCCAGGAGG AACAGTCATTGAGCTTCTAAGTCTGGACACCTCAGGAGGGTCAGCCACAGGGGGCACCCA CTGGTCAGGTGTATAAGTTCATTTAGGGCTCGTAGTTCCTAGTGAAGCCGAGCGGTGCCG TTTTGCACATAAGGAAGCAGTGACGGGGACAGCACAGTGGCCCATCTGCCTCTTGCCTTG CTCTTCACCAGGATGCCTGGTGTGTCCCTCCATGGCCAGGCTTTACAGAACGCAGTCCCA CCTGGAGCAGCCACTCGGACCCAGCAGCCCCCCATTGTTGCCTGCTCCAAGCCTCACATC TAACCCTAGCTGCGGCTGTCTGCTGGGAAGAGCCAAGTCCATAGGGCCCTTTGGGCACAT GGCCAGGCCTCTGACCCTGTGGCTGCTCTCTAGTTCTCAGGCCCAGGCAGGATGTCAGTG CAGGATGGAGCCCCGCCCTACCAAAGGCTTCCAGGTGGGCATGAGCTCACAGGCAGGCCA GGGAGTAGGGAAAGGCTGCCCTGGAGGAGGCCACCATTGGTGCAGATTCTTGGTCCCCTC TACCCCCACTGCTCCAAGAAAAGGTGGCCTAGGGGCATTATAGATTGGGAATTGAGGGGT TGGAGTGTTAGTTCATGCCCTGGCCTGGGAATGGGACCGCCCTACCAGGTTCGTCTCCCT GCCAACCCCAGTCCCTTCCAGTGCTCTCCTTTCTTTCCCAGGAGACCCCAGCAGCTCCAA CACCCGCCGGCGCCACTGGAGGCAGCTCAGCCTGGCTAGACAGCAGCTCTGAGAATAGGG GCCTTGGGTCGGAGCTGAGTAAGCCTGGCGTGCTGGCATCCCAGGTAGACAGCCCGTTCT CGGGCTGCTTCGAGGATCTTGCCATCAGTGCCAGCACCTCCTTGGGCATGGGGCCCTGCC ATGGCCCAGAGGAGAATGAGTATAAGTCCGAGGGCACCTTTGGGATCCACGTGGCTGAGA ACCCCAGCATCCAGCTCCTGGAGGGCAACCCTGGGCCACCTGCGGACCCGGATGGCGGCC CCAGGCCACAAGCCGACCGGAAGTTCCAGGAGAGGGAGGTGCCATGCCACAGGCCCTCAC CTGGGGCTCTGTGGCTCCAGGTGGCTGTGACAGGGGTGCTGGTAGTCACACTCCTGGTGG TGCTGTACCGGCGGCGTCTGCACTAGTGAAGCCCTGGGCTCTTCCCACCACCCATCTGTT CCGTTCCTGCAGTACACCTGGCCCCTCTCCGAAGCCCCTTGTCCCTTTCTTGGGGATTGT GGAGGCTGGGTCAGAGGGGAGTTAAGGGACTGCAGGCCTGGCAGCAGGACATGCCTTGGC TGAACCAAGTCCTGAGAGCAGCATCTCTGTCCCCACGGTGCCTTGTGTGGGTCCCCGTCC TTGGCTTTCTGGGTCCTGGGCTGCCCCCAGTGCTCCAGACCTTCCCCACTGGCAATCCAG GTTATCATCCATGTCCTCCAGAGGAGCTTCCTCCTCCAGGCCTCAGCCCTGTTGGCCCAG GTGGAGCAGGAGGGACCACTGGAACATGTGGTGCTTGGGAATGCCTCTCCTGTTGCATTG GTCCCTGAAGGCCTCAGGGCAGGTATGTGGTGTGTGGGCGACTCCACAAGACCTGCCTCC CATCCTGGCAGCCCAGCCTGAGACCGTTGCATTGAGGCAGGCAGGAGCGGCAGGGTGGCT GCTCTCCAGGAGCCCAACTGCCTTGAGTTCCTGCCCCACTGGGCCCCCTCCCCTGCTGGG CAATCCTGGGAAGGTCTGGAGGTTCCTGTGGACCTCAGGGAAGCCAGGGGCAGCTGTCAG GCCTGAGGAAGACCTGTGGAGCTCCTCTCCAGCCTCCTCTTTCCCTCCCCTCTGGTCTCC ATTCTCTTCAGCTCCCTACATGGGCTGGGGAGGAGACACCTGGTGGGCAGAGCTCAGGCA GAGGTTTGGATTTCAGCTCCCTCACTTCCGGGGCTGTGTGGCTTTGGCAGATGTCAGACT TCTGGTCTTGCTTCTCCACGTGGACAGTGAGTATCTGGCTCATTCTTCACTGGGTTCTTC TGAGATTGAACCTACAGGTGTTTGCCAAGTGCCTGGCCCAGAGCAAGTGGCCACTGCTTC TCCCATCTCTCTCCTGCCCAACCTGGTAGAGCTGAGGGCATGAGAGGCAGAGTGCACAGT GGTCAAGGGTGCAGCTCTGCAGCACAGGCAGCCTAGGCCTGCGTCCCAACCTGCCTCTCA CCAGCTCTGTGACCTTGGGCAAGGGATTTATCTGTCTGTCCCTTAGTTTTCTCACCTGTA AAAGGAGGATAAGTATATATATATATTTCCCAGTGTTGTGAAGATTAAAGGAGTTTATCG ATGTAGGTCTTAGGATGAGTCCTGGCATTTACCAAGGGTTGGATATATGTTATTATCACT ATTAAGTGTTGAGGGTCCAGGCATGCTGGGCAACAGGGACCCCATCTCTACAAAAAAGTT TAAAAAATTAGCCAGGCGTGGTGGTGCACCTGTCGTCTTAGCTACTTGGGAGGCTGAGGT GGGAGGATCACTTGAGCCCAGAAGCTTGAAGCTGCAGTGAGCTAGGATCGTGCCACTGCA CTCCAACCTGGGTGAGAGAGCGAGACCCTGTCTCAAGAAAAAGAAAAATGCAGAGAAACA GGAGTCTTGGCTACTCCTTTAGAGGCAGACTCAGACCCTCCTGCCTCACAGCTTTATCTT TGTATTTGCCCCTTACTTTATCTTGTGCCTTGAGAAATTGCTGGGGAGAGAGGTATGTCC ACTGGGCAGCTGTACAGGATGGAGGATATAGGGCGTTTCCACTCCCAGCAGCCAGGTTCC CTCACCCCAAGCTCACCCACTGTTGGGGAGATTATCTACAATAACACCAGAAACACATTG GGGTGGATTGGGGGTATCCTTATGGGTTCTTTTCAGGGAACCATTGCTGGACAAGGCACA GGAGCCACCTCCATTTCTGAGCTCTGCAAGGGACAAGAACTAGAGCCATCAGGGGCTGGG CTCACTGTGGCCCCACCCCAAGCCGTCAGCCTCCAGGGATCTACACCCTGCCTTGGCTGC TACAGCTTTTTCACTCCACTGCCCTAGGGGAGTTCAGCAACCTAATGATCTCTATCTCTG AACATCTCTTCATCCCATGCTCCAAGTCCAGCAACCTGCACCCTGGAACCAGGAGTGGAC CCTACCCGAGCTGTCTGTATTAATCCCCATCCCCCACCACCAATCTTAAAAAGCCCTCTG TCCCCCTACCCTAAACCCCAGTTAGGTACCCATGCTGGGCAGGTCAGTTAACAATTTATG CACAGGTACTAGTTTTATTGTATTACCGTTCCAGGGTAGCTTTGAAAAAAGTATCTCAAA AAGGCAACATGGGCCGAGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCA AGGTGGGCAGATCGCCTGAGGTCTGGAGTTCAAGACCAGCCTGGCCAACAGGGTGAAACC CCGTCTCTACAAAAATAAGAAAATTAGCCAGGTGTAGTGGCAGACGTCTGTAATCCCAGC TATTCAGGAGGCTGAGGCACGAGAATTCCATGAACCCAGGATGCGGAGGTTGCAGTGAGC CGAGATTGTGCCACTGCGCTCCAGCCTGGGCGACAGAGTGGTATTCTGTTTCAAAAAAAA AAAAAAAGGCAGTATGTAGCCCCGAAGACTGTTGCCCAAGTGGTAGAATGTTAGCACACT ACCAGCCTAGGTAAAAAATACAAAAAGTAACTGGGCATGGCGGCGCCCATCTATAGTCCC AGCTACATGGGAGGCTGAGGTGGGAAGATAAGTCACTTGAGCCCGCCAGGAGGCGGAGGT TGTAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGACCGAGTGATACTCTGTC TCAAAGAAAAAAAATTATAATTTTAGCACAGTAACCAGCCATGATGGGAGATACCCTGGG TAAGGCATGTAGAAAGGGTTGAGGGACCTTCCCAGTCCCCTAGCCCCGCCTCCCATCCTC CCATCTTTTTCTTTTTTCTTTTTTTTAGAGAATCACCCAGCCTGGAGCGAAGTGGTGCAA TCATAACTCACTGTATCCTTAAACTCCCGGGCTTAAGCGATCCTCCTGCCTCAGCCTTCT GAGTAACTAGGACTTCAGGTACCTGTCACCATGCCTGGCTAATTAAATTTTTTTTTCTTT TTTTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTC AGCTCACTGCGACCTCCACCTCCTGGGTTCAGGCCATTCTCCCGCCTCAGCCTCCAGAGT AGCTGGGACTACAGGCGCCTGCCACCACGCCTGGCTAATTTTTTTGCACTTTTAGTAGAG ACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCCGC CTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCAAATTAAAT TTTTTATAGAGATGAGGTCATGCTGTTATGTTGCCCAGGTTGGCCTCATGAGATCTTGCC TTAGCCTCCCAAAGTGCTGGGATTACAGATGTGAGACACTGCACCCAAACCCCACCACTT TTTTTTTTCCTTTTTCTTTTTTTGAGACAGTCTTACTCCGTTGCCCAGGCTGGAGTGTAG TGGCATGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTC AGCCTCCCGAGTAGCTGGGATTACAGAGGCCTGCCACCACACCCGACTAATTTTCGTATT TTTAGTAGAGACGGGGTTTCTCCATGTTGGCCAGGCTGTTCTTGAACTCCTGACCTCAAG TGCTCCACCTGCGTTGGCTTCCCAAAGTGCTGGGATACAGGAGTGAGCCACTGCGCCTGG CTGATCCCAGCACTTTTCAAATGATGCCGCTCAAAGCCGTGACTTGGCCTACTTTGAACA GCAAACTTGTTGCTGCTGTTGTCAACCTGAAGGCCTCTCAAATGCCAGCTTCAAGCAGGG TGTGAATTGGCCAGTGTCAGATCTCAGGAGTCCTGTGTTGAGAGTGTGGCTTTCAGCTGC GGGGAGCTGCACTTGGTGGGGAAAGCCAGGCAGGTCACCCTCACAGCCAGATAATGTGGA GGTCAGAACCCAAGGAAGGGAGTGAGACCTCCACTCCCAGTGGGGGACCTGGCCACCCAT CCTTGGGGACCTGAGAAAGCGTACTTCACCTTGGGGTGAAGGCTGGGTGGGGCCAGAGGG ACCAGTGCCCTCCTCAGTGCTTAGGGGCAGAGCCACCTGCAGCAATGGTATCTGCATATT AGCCCCTCTCCACCTTCTTTCTCCCGCTGAATCATTTCCCTCAAAGCCCAAGAGCTGTCA CTGCTTCTTTCTCCCTGGGAAGAATGCGTGGACTCTGCCTGGTGATAGACTGAAGCCAGA ACAGTGCCACACCCTCGCCTTAATTCCTTGCTAGGTGTTCTCAGATTTATGAGACTTCTT AGTCAAATATGAGGGAGGTTGGATGTGGTGGCTTGTGCCTGTAATCCCAGCATTTTGGGA AGCCGAGGTGGGAGGATCCCTTGAAGCCAGGAGTTTGAGACAAGCCTGGGCAACAAAGCA AGACCCTATCTCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCTAG GAGATGCTCTTTACCCTGCCTGGCCTCAAACTATTAATAGCTTCCTTTGAGCAACATTAT TTATTATGAACTTTCAAACACAAAAAAGTAGAGAGAGTAGAATAACAAATCCCCATGAGC CCATCACCCAACTTCAGTAATTATCAATTCATGGCCATCTTGTTCACCCCTGCCTGCTTC CCTGCTTCCCCTCATTCTGCAGAGGTTCTTTTCTTTTGAGACAGAGTGTTGCTCTGTTGC CCAGGCTGGAGTGCAGTGGTGCAACTTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAA GTGATTCTCCTGCTTCAGCCTCTCAAGTAGCTGGGATTACAGATGCCCGCCACCACACCT GGCTAATTTTCGTATTTTTGTTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCG AACTCCTGACCTCAAGTGATCCGCCCGCCTTGGCCTCCCAAAATGCTGGGATTACAGGTG TGAACCACGGTGCCTGGCCACTGTACAGGTTATTTATAGAAGTTGGAGAGTGAAGGGTTG AGAAAGCCAAGGGGCAGATGCGGGTCTGGAGGATTTTGTGCCTAAGGCCCTCTCTTTGCT CCCAGACAGCATGAAGTAACAATGAGGCATCCACCTCTTGGTTTTGTGGCCTCTGTGGAT GACGTCTCTCACCTTGAACCAGTTCAGAGTTGGAGTAGCGCAGGATCCTGTCTTCAGAGG AGGGGCCGAAGCGGGTTCCTCTGTTGTCAAGCTCTTTGGAGGTGCCTGGCTGCTACTACT GTCCCAGAGAGGTGATGATGAATGATGGGTGTGTCCAGTGGCAGTTTGCCCCACTGAGGC AGGGGCTTCCACTAGGCCCTGACAGAGCCCTTCCAGCAGGCAGAAATCCCTGTGCTAGGC AAGATTCAAACTCCGTAGCATGTCTCCTGCTCCCATCTCTTAGGAATGGAGTCCTTCAGG CCTTGAGTCCCACATTTTCCATGATGCTCCATTAAGCAGCTGATAGCACCCCCACCTCCA GGGAAAGTGAGTTCAGAGTCCTTGGTCTAATGCATCTGTGTTGAAATTGAGGCCTTCCCC TGTGTTCACCTTTCTGCTCTTTTTCTTTTAGCCCAAGGCTATGAAGGCCTCATTCGGTGC TGGGCATGGTCACTCCTAGCATTCCTCACTCTGTTGCTAACAGCAACAGCAATAATAATA AGGGTTACAACTTACTCCATACCTTACTGTCTGCCAGGCATTAAGCTAAGTGCTTTACAT ATATTAAGTCATTTAATCCTCATAATGACCCTATGAAAGAGATACCATCTCAACCCAATT GACAGCTGGTTTGCAAGATTAGGAGGGATGAAGGACCCAGGGGACAATGCGAGGGAAAAC TCTGACCCCGGGGCCCCAGGCTGGATGTTCTTTATGCCTGTGAACCACAGCTTATCACAT GTCTGGAGTTAGGGACCCCACTTAAAGTGAGATTTTGGCTGGAGGTGGTGGATCATACCT ATAATCCCAGCACTTTGGGAGACCAAGGCAGAAGGACTGCTTGAGGCCAGGAGTTCAAAA CCAGTGTAGGTAACAGCTAGACCCTATCTCTACAAAAAATTTAAAAATTAGCTGGGTGTG GTGGTATGTGCCTCAAGTTCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCA CAGGAGTTTGAAGTTACAGTGAGCTATGATGGCACCACTGCACTTCAGCCTAGGCAACAG AGGGAGACCCTGTCTTTAAAGTACATAGAGGTTTTTCACACCAACACATCTCTGCCCAGT GTGCCAACATCTGCCACCTGCTATAATAGTACTATAACACTCAATATGTAATTAATGTAG TCTCAGGGATGTTATGACAATATGATTACAACTATCACGTGTGTGCCCAGCCAGGCTCAA TGCCCCAGGCTGGGCGAGGTGGGGCAGGGGACACAGCCTAAAATGCCAGGCCTCAGGAAG CCATTTGGTTTAGCAGACATTGTTTATTAAAGGAGTTACCTATGCCAGATCGAAGGCCTA AGATGATTAAGACACTATGAGTGCCTTCAAGTGGTTGGGGACGTTCATGATTGTGGTACA GACAAATAGGCTTTCACATCATTCTTTTATGTAATCATACAACAGATATTTGCACCTACA TGTGCAGAGCACTGTGATAGGCCTCAGTGACACAGAATAATACGGCAAAGACCCCACCCG ATGAGCCCCCTCCCACCACCCACCAGTACAGTAGGGGGTGGTTTAATGGAGTGTTCCTGG AATATGAAGTGGGGGCAGGCATTAGGGGTGGCAAAGGGACAAGTGTTTATCTGATCAGTT ATGTACTGTTTATAATAAGTAAATCAGCAGAGGGGGAATAATACTTAGAACCTATAGAGA GTAAATCTGACAAGATGAAATGCTGATGAAAATATGGAGGAAATGAAACTCTCATGGGTT TTGCAGGGAATCTAAGTCAGTGCTGTGTTGTGAATGTAGGTGTACCCTTTGAATTCATAT GTTGAATCCTAACCCCCAAAGCAATGGCATTAAGAGGTGGGGCCTTTGGGGCTGGGTATG GTGGCTCATGACTGTAATCCCAGCACTTTGGGATGCTGGCAGGGGGCAGATCACTTGAAG CCAGGAGTCTGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTGTACTAAAAATACAA AAATTAGCCAGGTGTGATGGCGTACATCTGTAATTTCAGCCACTCGGGAGGCTGAGACAG GAGAATAGCTTGAACCCAGTAGGTGGAGATTTCAGTGAGCCGAGATCGTGCCACTGCACT CCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAATAATAAAGATGTGGGGCCTGT GGGAGGTGGTTAGGTCATGAGGGTGGAGATCATGAATGGGGTTAGCACCTTATAAAACAG GCTTGAGGGAGCCCTTCTGTCCCTTCTACCATGTGTGGATGCAGTGAGAAGGCACCGTAT CTCTGAAGCAGAGAGCCCGCCCTGGACACTGGATCTGCTGGCACCTTGATCTTGGACTTC CCAGCCTCTAGAACTGTGAGAAATAATTTTTTGTTGTTTACAAATTACCCAGGCTAAGGT GTTTCATTGTAACCTGAATGGACCAAGCTGGTGTGACCCTGTTGGAAAACTGGCAGTATC TACCAAAAGCCGAACATACGTATAAACTGATCCAGCAGTTCCACTCCTGGGTATGTACAC CACAGAAAGCTATGTCCACCGAGACATTGGCAAGAATGTTTCTAACCACACGCTGACTGT AGCCCCAAACCTGAAACAACCCAAATGTCCATCCACCAACCCAAATGTCCATCCACAGTT GAAGCTACAGTGAAGTCACAGGGTCGAATACTACTGCACAGCAACGAATATGAATGAAAA TATCGCTATGCACAGCAACATGGATAAATTTCACAGACATGAGGTCAAGCAAAAGAGGTC AGAGTCCTCATCATCAAGAGAGAATTCATTGTATGATTCTCTTCCTACAAAAAGTACAGA AATAAGCAAAACTGATCCATGGTGTTAGAAGCCAGGGGAACAGTTAACAGGGGAGGGATA CTGGGGAGGGGCATCCTGGAGTGCTGGTCTACCTCATCTGGGTGTTGATTTCACGAGTAT TGTCAGTTTGTTTCCAGACTCCCTGTTGGAGATGTGGAAATAAAAACCACCTAAACAAGA GCAGAGAGGCCATTTGGTCAAAGTTTGCAAAGGAGTCAGCCATGATTGCTTGTATTTGGC AGGGGTCAAAGGCAGGCAGGGACTGTGAAATGTTATAGTGGAAAAAAAGGGAAGGCTCTG GGTGTGCTGTGATTGGAGATTGTTGGCATGGGGACAGAGCGGACTAACTGGAGGGGCATC TTTGGTTGGTTGGGGGGGTATATTTGGCTTTCTCTGGTTGGTCTGGAGTTGGAAGAGGGG GTGTGGTGGCTGGGGATTGGGAAGAAGCTGGCAGCCACTAAGTTCAGACTGTTCTGGGTC CGATTGCTGCTGAGGCTGTGGTTTGGCTTCCTTGGCTTCCCAGGCTGGTCATGGGTTTCT GGCCAGAGTCTATTGTCATATGTGGCCTGGCCATTGTCCAGTTGTATGTTCAGTCTCTTG GAAGGAAGGGTATTGACTCTGAGAGGGGCCACCATCGCTGGAATGGGGGACACACAGTAC TTCCTCCAGCTGCCTACACCCCCCTAGGGTCAGTGGCGCCTGCCTGTGAGGGTGAGCCCA ATGGCTAGAGGGCTCTGCTCCAAGTCATTGCTTACTACACCCACAAACATTCTTCGTTCT TTAAGGCCTAACTTAAAGCCCAGATCCTACAGGAAACCTTGATTAGACCCCTCTCTTTAT TAAGCTTCCTAAGATCAAACCCTGCTTTTGTGTAAATGCTGACCTCCTTGCCTACATTTT AAAAACCTAGAGCTGGGCATGATGGCCCCAGCCTGTAATCCCAGTGATTCAGGAGACTGA GGTGGGAGGATTGCTAGAAGCCAGGAGTTCGAGACCAGCCTGGGTAACATAGCTAGACCA CATCTCTTAAAATAAAATAGTTAATTTAGCCAGGCATGATGATATATGCCTGTAGTCCCA ACTACTTGGAAGGCTGAGGTGTGAGGATCTTTGAGCCCGGGAGGTCGAGGCTACAGTAAG CTATGATCTCACCACTGTACTCCAGCCTGGGTGACAGAGCGAGACCCAGACTCAAAAAAT AAAAATAAAAACCCTGAATATCTTCCTTCTACTTCTTCAGTGCTGTTTTTATTTAAAAAA AAAAAAAACCAGCCAAAACCACAACTTTTTACTGAAGTGTAATGTAAATGCTGTAAAAGG CAGTGAAAGGCACAAGGGAGGTGGAGGGGTAGGAAGGGTGGAAGTGGCGGGAGGAAGTGG CAGGGCAGGCAAAATGAAGGGAAGCCCTGGGTTCTTGTCCTGCATCCGCAGCCAGCTCCC ACTTTCCTCACCCTCCAGGACCTGTAAACTGTGAGGCTGGACCAGTTATGTCAAATCTGT CCTCCCCCAGAGCTCAGTCCCTCTGCCCTTGGGTGTCCTTGGCACAAGGCAGGCTAGGCT GCACCAGCTTCCTCCATCTCCGTCCTGCCTCCCCCATCCCCAGGTGCCATTCCCACACCA TCTGAATCACTGATTTCCTCGCAATCAGACGCTATCTTCCAGTTAATCACTTCGCTTGTA TTTAACATAAGAAAGAAAAACCCTTTCATTATCACATACAGCTGGAAATCGGCTTCTTGC AGGAGGCGTATCCAAAGGAATTGGAGAAGAGATAAACTGGTAATTGGTGAAAGAATTACT TTAATTTTTTTTCCTACTTGCTGTCATGATGATGTCCTTAGAATTGTGAGCCCGTGGACA CTTCTGTACAATAAATCTGCTATTATTACTTCTA OMIM ID 609676