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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MKL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57591
Official gene symbolMKL1
Full namemegakaryoblastic leukemia (translocation) 1
Aliases,BSAC,MAL,MRTF-A,
Gene summaryThe protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q13
Gene position41032690 - 40806292  Map Viewer
Gene orientationminus
Gene size226399 bp
Gene sequence
OMIM ID606078