Entrez gene ID | | 57715 |
Official gene symbol | | SEMA4G |
Full name | | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
Aliases | | ,FLJ20590,KIAA1619,MGC102867, |
Gene summary | | Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene and the gene for mitochondrial ribosomal protein L43 overlap at map location 10q24.31 and are transcribed in opposite directions. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q24.31 |
Gene position | | 102732286 - 102745372 Map Viewer |
Gene orientation | | plus |
Gene size | | 13087 bp |
Gene sequence |
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