Entrez gene ID | | 57728 |
Official gene symbol | | WDR19 |
Full name | | WD repeat domain 19 |
Aliases | | ,FLJ23127,KIAA1638,ORF26,PWDMP, |
Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p14 |
Gene position | | 39184024 - 39287430 Map Viewer |
Gene orientation | | plus |
Gene size | | 103407 bp |
Gene sequence |
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OMIM ID | | 608151 |
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