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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for G6PC2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 57818 Official gene symbol G6PC2 Full name glucose-6-phosphatase, catalytic, 2 Aliases ,IGRP,MGC141936, Gene summary This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq] Location Chromosome: 2   Locus: 2q24.3 Gene position 169757750 - 169766510  Map Viewer Gene orientation plus Gene size 8761 bp Gene sequence >G6PC2:87867..96627:Length=8761 TCGACATGCCACAAAGGCACAGTATAAAAACGGTGGGAATCAGAGCACTTCAGCTCCAAT TGCTCTATGTTTAGAATTGCCTCTTTTTCAAGATGGATTTCCTTCACAGGAATGGAGTGC TCATAATTCAGCATTTGCAGAAGGACTACCGAGCTTACTACACTTTTCTAAATTTTATGT CCAATGTTGGAGACCCCAGGAATATCTTTTTCATTTATTTTCCACTTTGTTTTCAATTTA ATCAGACAGTTGGAACCAAGATGATATGGGTAGCAGTCATTGGGGATTGGTTAAATCTTA TATTTAAATGGTAAGATTTCTGTTTTATTTCATTTTTTCCTAAGATTTATCCTTAAATTT GTGACTTCGGCATAATGATCACATTTCAGATGTATATCGTTTTACTTGGAAAATCTTTCA AAAATACCAGGTAACTTGAAACACCAGATTCATAAGTAGAACTTTTAAAAGGCACAGAAA TGTATATATATGTTTTTGTTTTTTTTTTTTTTTTGAGACAGAGTTTTGCCCTTGTTGCCC AGGATGGAGTGCAATGGCGTGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGC AATTCTCTCACCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACACCCAG CTAATTTTGTATTTTTAGTAGAGACAGGGTTTCTCTATGTTGGTCAGGCTGGTCTCTAAC TCCCGACCTCAGGTGATCCACCGACTTCGGCTTCCTAAAGTGCTGGGATTACAGGTGTGA GCCACCACGCCAGGCCAGAAATGTGTACTTTAATGACTTATAAGTAATTCCCAAACCCCT GTAACACATATTCTGTGATTAAGAATTACTTACATGAGCAGCGTGATAATGAACAAATTG ATAATTCTAGGGACAAATTTTGATATTTCCAGTCTAAGTATCCAAAGCACCCATAAGACA TTCCCTGCAAGGGAAAAAAGCCCCCATGTTCATGGGAAACCAGGGTGCCAAAATACCAAA TGGCTACCACCTTTAATAATGTGTGAGAGACCAAGACCTAAGTTTTTTCAAAGTCTCTTA ATCATGAACTTTCACAATTAACCCTGCGCTTGAGTCATTTTTTATAGGAAAGAATTGCTA ATCTCCAATTAAATAATAGCTGTGTATTTAAATATATATGCATGTTTATAATTCTTTAAA TACAGGATATTATTTGGTCATCGACCTTACTGGTGGGTCCAAGAAACTCAGATTTACCCA AATCACTCAAGTCCATGCCTTGAACAGTTCCCTACTACATGTGAAACAGGTCCAGGTAAG CTATTACAGCAGGCTCCAGTTACTGAAGATCTTCCAATAGAGAATCATTACACAGGGTTA TCATCTAGGAACTGATATTATATAGGGTAGTAAAGAAAATCTCATGAGTGAGGATGCTAA AACTTCATAACAATCAAAATTACTAATGAGGAAGCAAAGCAAAAAAAATACTCAAATTCC ATTTTGTTATTTATGAAAGGGTAGATTGGGAGAAAACTCCCCCAGTGATTAAATATTTGG TGTTTACTTTTCAGAAGAATATAATGACTTGATACTAAAACAAGAAACAGTTAACTAGAA CAAATTCTCAAGGAACTAGACTAAGATCTTAGAAATGTTGGTTAATCTGCTGCTAAGCAA CTTTCAAAGTTACTATAGGTCTTCCGAGTATCTCACGAATGAGGGAGGAGTAGACAAGTC TTCTGTAAGAAAGGTAAGGACTTCTCAATGTTACTATAGCCAGTAAAGACTATTTCTAAC CCTAGAACAATCTCTTTAAAACATATTTTTTCTCTGTACACAAGTAGGCTTCTTGGGCCA CTTCTTTTTTATTCTAGGTAAGATTCTGTATGAGTATAAAATCTTTATTGTGATAGTTGA TTCTAAGACTGTTTTAAAAAGTTTTTTGAAACATATATTTAAAAATTACATTTTAATTTA TAAGAATGTGTTATATTGTACCTCATCATTTTACATAGCATAACATTCTCGCCAGTTGAC ATCCTTCGAAACTAACTTTGAGTAAAGGGTAGTAGAGAATGTGTAAATTCTTAATGAGTG TTCTGAATATGTCTTTTTTGTTCCCATAGAAGTATACATACATCTGTTATATCGCTTATT ACACTAAATGATATTAACTAATTCTTTATATATCCGATTGCCTAGACTGGGTGTTCCATC AGGGGAGGGATGATGCATAGTTTATCTTTGTGAAACCAAAGTGTGATAAATGGATGAATG GTTGGATGGGTAACATTTGAGACCACCGAAATGTTATCGTGGTCAATTCCAGTCCTTTCC GGCATGTGTTCCACCTTATAAGACATTTTCTGGAAAGAGAGAGAGAGAAAAGAAAGAAAG ACTGCATCTCTCGGGGAGATTTACAATTTTTTAAGGCATAGTTTTTAAAAGGCTCTGAAA ATTCCTGCAGATAAGAAATAGGTCTGTCTTTGTTTAACAAATAAGAGACTGGTATTTAAT TTGAATGAACTACCAGGTGAAAAATCGAGGAGGACATTTAAGGAAACTAATAAAAAATTC AGTAGCATGGAAAAGGCATTCTGGAAGTAGAAAGGCTTTTTCTGCTAGGATTAATGCCGT CTTTATAGCTTCTCCTCATCCTCTGTTTTAAAACAAAGATTCTCACTGCAGTGGCCACAA GATAGGCATAGAAGTAGCTGCTAGTACACAGCAGTCATTTGTAAGTCAATCAGCAAATCA CTGGCATAGCAATGATATCCTTTAGAGTTTGACTTCTCAGCCCAAGGAAAATAAGCCAAC TGAAGATCCAATACAAGCATTAGGGTGGTGCAAAAGTAATTGCGGTTTTTGCCATTACTT TCAATGGCAAAAACCGCAATTACTCTTGCATTAACCTAATACTTTTGCTTGTCAATTAAA AACAACCAAATATTGAAGAATGAGTAGGGCTGTGGCAGATTTGGGTGCAACTGCCTGAGT TCTTAATTAGCCTTGAGTATATTGATTTCTGGAATTCAATGAACCTGAAAATCTGGGAAA AAAATTTTTTGAGACAGTGTTTCTCAGGCTCAATTTAACTCAATTTTTCTTATTTCTACC CACTTCTAAACATTACATATAGCCTGTGTCTTGTCTTTTTTTCTGAGTTACTCATAATTT TCATGGGGAATATGCTATTCTATTATTCATTTCTGATCTTGATAGTTAACCACTTTTCAA ATGGACGGACACTTTGTTGTTGCAGGAAGTCCATCTGGCCATGCAATGGGCGCATCCTGT GTCTGGTATGTCATGGTAACCGCTGCCCTGAGCCACACTGTCTGTGGGATGGATAAGTTC TCTATCACTCTGCACAGGTCAGCTTTGCTGCAGTTTCTGTAGCACTGGAATATGACAGTT TTTAATACAGAAAGTCTTGTCTAAAAATTAATTTTAGTGCAGTTTTAGTCAATGAATAAA ATGTGCTTATTCTATTCTTTCATAGACAAAATAACAAAATGAATAGAAAACTAATATTTT GCTTTAAGATAATAGCCTAATTAGCTCATAGCTATTTCCACTTTTCAAGTTGGAAATGTT TAACTGATTAATGACTTGCTAAATGTGCCTCTGGGTTTCCAAAATGCAATAATTATTTTG ATAACTCATAAATAAGTCGTCTAAAATTATACAGCATAAGGAAACATTTTTGCATGCACA TTCCCTTGCTTTAAAATTAACTGGAAGTTTTGAGAATCATCATTCTCCTTGACTGCATCA GTTTATTCAGTAAAATTATGCTTCCTTCTTCGAATAGCCAATGCTTTTGATTTCAGTAAC ATATATTCCAGCTTTATAGAGAGCACAAACTTTTTAATTAAAAACATTCTGGAAGCAAAC TTAAATTTGAATGTTAGTAGATTTAATGTTAGTAGGTTTCTTAATGTTTAGAAAGATCTA GAACTTAAAGGTTACTCACAGTTGCTTAGAAATTGGGTTGTTTCCTTCTCTTCTTTCCTG AAATACTTTGTCATTAAAACAATCCTGAGTACCAATTTAGCCATAAATTAGGTGACTTGA AATTAGATTTGCAAGTTAACCTTAAAAAAATACTGTAACATATGCCATTATTAAAAAGTT TTCTAAAATAAAAAAAGTCAAGATCTATCACATATTCCACTTGTTAGAGTAGTATTGGAT AATATAAAAAACAAACAACTAAAGGAATTTGGGTGTCTTAAAAGTTTATTCTAATGAGAC TGTGACCTGTATGCCTTAATGTATTTATTGCCCAACCCAAAACAACAACATAAAAAGGTG CTATAATGTAAAAAAGTTAGCATTTTCTATTTACAGACAATTTTCAAAGTAGGAATCTAG GTCAGTTTCACCTTTTCTCTATACTGTATTCCTGCCTCCAATGACCAAACCTGAAAAAAT ATGTTTCTTCTAAGAAAAAAATTCTCATAACTCCTTTTTAGTTTTTATAACTGCAGTATT TTCTTCATCTATAAAATTTTACTGAGTGTGTGCTTCTTACCTTTACATTACCAAATTCTT GTTTATTCTTCTTCCACATTGGTATCCCACTTACTTCTTCTTTCAAAGCCTCATTTCTCT GTGTTCCTTAGCATTTATATAACCAAATTTCAGTCTGATTATCAGGAACAAACCATTCAA GGATTCCTAGAACTCAATACTGCTAACACTTTTTTTTTTCAATGACATGCATTGCTTGGA TTTTAATATTTTTTTATGTTTTTTGTGCATTGCTGTTTTTAATCCAAAGTGTATAACCTA TAGGTCAATTCCCCTGTTCTCTATTTTCTGTGTCTCAAAAAAAAAAAAACAAACAAAACA AAACCCAAAACAAAAGAAAAAAAAAAAACAAGAAACAAGGACTTTTGAAAATCTGTGCAA TTAAACCCAATGAAAAAATTTGCCCCAGATGGAATGCTCATGCGCTTTTCATCTGGATGG TAGCTGCGTTTCTACTGAGTTTTCCTCAAGCAAAGAAAGGTTGAGAGAGGAGGCACATAG GGCAGGGCGTGAAAATATATATGGTTCATTCTTGATCATTCTGGATATTAGTAATTCCCC CAAACTTGAATTTCCCCTACTCCATTAAAACAGTTATTCTTATTTAATGGATGTCAAAAT GACTTCCTTTTTAACATTTATTAAATCTCAGTATATAGCACTGGTTAAATTTAATGCATT GAGAAATGTAGAAATCTCTGTTAAAACTTCTCAAATCCTATGGGGTATGTGGAAACAACA TTTTGAAAAAAAAGATTCTAGAATCATGATGCTATGTCACAGTTAGAAGATTCTTCTGAG AAGGATCATCTGATGTCACCCCCTCTAATTTTGAGTGATCCAGTTTCTTTGCTTTTTATG CTTGTATCTATTCTTCCATCGTAGACTGACCTGGTCATTTCTTTGGAGTGTTTTTTGGTT GATTCAAATCAGTGTCTGCATCTCCAGAGTATTCATAGCAACACATTTTCCTCATCAAGT TATTCTTGGAGTAATTGGTGGTAAATATGATCACTTACCTTTAGCTGTGTCCTTTGAAAG CTTTAGTTTCATTATGTTTAAGGGTATCAGATTGTCCCCGGTAATCAACTTTCCAATTTC AGAGGTAATTCTGTGAAGTCACTGATACTAAATGCTACCCCGGGAGCTGACGTGGTACAA CACACCTCTCATAGCCTCCATGTACAAAGTGGCACAATCTCAGTGGCGTAAATGCACAAT TGCTTCATGAGGTAGGCTTTTCTGAAGTGAAATTAGAGCTAAGTCTAACTCCCAAACCAT CACTTCAGACAGTGTGCTTGTGTCTTGCGTGAGGGAACTTAATGACTCTGAGCCCTGCAC ACTGTGCCATTCTCTCTGAAACATGTGAAGTGACTATTACATGATTACGGACTCCATTTA GTAGCTGCTTTGTATTCCTGAAGCAGTGTTCACCATGACTCAGTTTCCATTGTTCAGCAC CACCTTACCTTTCAAAGGCTAATTGGCTATGGCAATTGAAATGTTAATTGCAAGTACCTA GATCAGTGCTCTGTCTAAAAAGCGGGTTGTCAGTCAGTGCCACCAACTCCAGAACGATCC TTCTGGACTAGTATGAATAATGAAAACACCGTGGGCAAACCTGCATTTTTAGTTACTGCC TAAAAAAGGCTTTGGAAAATGGATAGAACCTCTGTGTCTAATGCCCTTTGTCATTGAAAA CTGTGGCAAATCTTTAATGCAGAGAGGAATGATCCTCGAGGGGCTCAAGGGCACACAGTC ATTGTCAGTGTCTCTTTCCAATCCTCAGGCATGCTGGTGGCAGAGGCCTTTGAACACACT CCAGGCATCCAAACGGCCAGTCTGGGCACATACCTGAAGACCAACCTCTTTCTCTTCCTG TTTGCAGTTGGCTTTTACCTGCTTCTTAGGGTGCTCAACATTGACCTGCTGTGGTCCGTG CCCATAGCCAAAAAGTGGTGTGCTAACCCCGACTGGATCCACATTGACACCACGCCTTTT GCTGGACTCGTGAGAAACCTTGGGGTCCTCTTTGGCTTGGGCTTTGCAATCAACTCAGAG ATGTTCCTCCTGAGCTGCCGAGGGGGAAATAACTACACACTGAGCTTCCGGTTGCTCTGT GCCTTGACCTCATTGACAATACTGCAGCTCTACCATTTCCTCCAGATCCCGACTCACGAA GAGCATTTATTTTATGTGCTGTCTTTTTGTAAAAGTGCATCCATTCCCCTAACTGTGGTT GCTTTCATTCCCTACTCTGTTCATATGTTAATGAAACAAAGCGGAAAGAAGAGTCAGTAG AGTGGTGCCTAGAGTTAGTGCTCTGTGTCACAGATCACCCTTCTCCATCCACCAGTAGAG CCACAGAGTAGGCACAGACCAGAGGCTTCTAATCCGACTTCACAGAATAGCGGCACAGGC CCCATTCCCCATAGAGATGTTTAGTTTGGCCTTCGCACTGGTCTTTTTTTTTAATCCTTC AGTTACCAATATTTAGATACAAGAATATTTGACATAAAAATCGGAAGTTCTGTATTTCTT GAAAAATCTGATAGTATGACAACACAGAGCCTGCATCCCCAGCTGGAGACAACTGACCAG AGCTGCATACTAACAGTCCCCAGTAGGAGGCAAGGACTCCATTTTCTCACAGTCTTCAGC ATCCCAGCAGGAGCCCCACTATGATTCCTTTATCTTCTTAAGGCCAGGCTGCATCTGATT CCTGTTGACATTTTAGTGGGGACCACAGCCATATCCAGTTTCAGTTTTCAGATGAGGAAA TGGAAGCCTATTTAGGTAAAAGAACTTGCCTGGAGTCACGCCACCTTCAGAGCAGGAATT AGAACCCAAGGCTTCTGACACATATCCCCATTACACTGTGTGTTTGAGTGTGCACACATG CACATGCTTTTTGTTTGTATGTTTCCTTTTTAGAACCAGGGACTTGCTCTGTTGCCCAGG CTGGAGTGCAGTGGTGGATAGCGGCTCACTGCAGCCTCAAACTCCTGGCTCAAATGATCC TCCCTCCTCAGCCTCCCATTAGCTAAGACTACAGGTGTGCACCACCATGCCTGGCTAATT TTTGAATATTTTTTAGAGCCAGCTTCTTACTATATTTGCCCAGGCTGGTCTTGAACTCCT GGCCTCAAGGAGTTCCCTTGAGGATGTTCCACCCATGTCAGCCTCCCACAGTGCTGGGAT TGCAGGCTTGAGCCATTGTATTAATAGTTGGCCTACACTGTCTTTTGTTTCTTCATTTAC AAGAGGTAAAAATCAGTAAGAATGAATGCTTTCATTTAGATTCTATGATGACTGCCATAT AAATCAGCTACCTTTTCAGAAATGACATTGAAATACTGCATCCTCTTTGACTTATACCCC ACACATACATGCAGGGTCTAGGTGGGACCAACAGTGGCTCCAGATGTATATACACACGGG TCCAGGGACAACAGAACAGGCCAGGCTACAGTATGGACTTGAACCTCTGCTTCACTTCTG GTCTCTGTTTTACAGTAGTGCTCACCAATATTTCAATAAATTCTACTGAACTTACTCTAA TAGAACATTATTCAACCCCCAAAGACTTATCTCTTCACTATGACATCTCCATACTTTATT TTTAGGAGACAGACTTTCAAAACCAGAGAAATCAGGTGCCTTCCTCAAGGTCATGCTCCA ACCCAGGCCAACTATTAAATGCTTGCATCTGTTAGCTGGATTAGTCTCTATGTATACTGA ACTGTGATGAAAATCTATAGCTTTGTTTTAGAAAATTATTGTTGATGGACTATTAATATT ATATTAACAATTTCTCAGTAAGTGTGTTTTTTCCTCATTGAATCTAGGAATGCTGGGCTT TAAGTTGATAACTGTGTCATTTCAATCAAGTACAAGGATTTTGAGGCAGATTTTGCTAGA TATCTTAGTAATCCCCCACAATGTTTTATGTAACTCTTCTCAGAATATCAATACATTAAT TATTTTAGATGACATATTAAATAATCTATGAATATTAATGAAAACAATACAGTTGAAGTG AGTGTTGTTTAACATGATAGTAGCTGAGGATAACAAACCTCAAAAAATCAAAGTATTAAT TACTCCTTTCCAAGTATATGTATAGAGCATGTGTCATTGCTTTTATAAAACGCACTTAAT AGCTTTCTTTCTAAAAGGCAACTGAACTTTCTAAAAGGTAAATAAACTGAACTTGATATT A OMIM ID 608058