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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5793
Official gene symbolPTPRG
Full nameprotein tyrosine phosphatase, receptor type, G
Aliases,HPTPG,PTPG,R-PTP-GAMMA,RPTPG,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21-p14
Gene position61547243 - 62280573  Map Viewer
Gene orientationplus
Gene size733331 bp
Gene sequence
OMIM ID176886