Entrez gene ID | | 5793 |
Official gene symbol | | PTPRG |
Full name | | protein tyrosine phosphatase, receptor type, G |
Aliases | | ,HPTPG,PTPG,R-PTP-GAMMA,RPTPG, |
Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21-p14 |
Gene position | | 61547243 - 62280573 Map Viewer |
Gene orientation | | plus |
Gene size | | 733331 bp |
Gene sequence |
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OMIM ID | | 176886 |
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