Entrez gene ID | | 5798 |
Official gene symbol | | PTPRN |
Full name | | protein tyrosine phosphatase, receptor type, N |
Aliases | | ,FLJ16131,IA-2,IA-2/PTP,IA2,ICA512,R-PTP-N, |
Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q35-q36.1 |
Gene position | | 220174143 - 220154345 Map Viewer |
Gene orientation | | minus |
Gene size | | 19799 bp |
Gene sequence |
| |
OMIM ID | | 601773 |
|