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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PURB (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5814 Official gene symbol PURB Full name purine-rich element binding protein B Aliases ,MGC126784,MGC126786,PURBETA, Gene summary This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq] Location Chromosome: 7   Locus: 7p13 Gene position 44924960 - 44915892  Map Viewer Gene orientation minus Gene size 9069 bp Gene sequence >PURB:complement(44905892..44914960):Length=9069 GGCGGCCTAGAAGATGGCGGACGGCGACAGCGGCAGCGAGCGCGGCGGCGGCGGTGGGCC GTGCGGGTTCCAGCCCGCGTCCCGCGGCGGCGGCGAGCAAGAGACGCAGGAGCTGGCCTC GAAGCGGCTGGACATCCAGAACAAGCGCTTCTACTTAGATGTGAAGCAGAACGCCAAGGG CCGCTTCCTCAAGATCGCCGAGGTGGGCGCGGGCGGTTCCAAGAGCCGCCTCACGCTGTC CATGGCGGTGGCCGCCGAGTTCCGCGACTCGCTGGGCGACTTCATAGAACACTACGCGCA GCTGGGCCCTAGCAGCCCCGAGCAGCTGGCGGCTGGCGCCGAGGAGGGCGGCGGGCCGCG GCGCGCGCTCAAGAGCGAATTCTTGGTGCGTGAGAACCGCAAGTACTACCTGGACCTCAA GGAGAACCAGCGCGGCCGCTTCCTGCGCATCCGCCAAACGGTCAACCGCGGCGGTGGCGG CTTCGGCGCGGGCCCCGGGCCGGGCGGCTTGCAGAGCGGCCAGACCATCGCGCTGCCTGC GCAGGGCCTCATCGAGTTCCGCGACGCGCTGGCGAAGCTCATAGACGACTACGGAGGCGA GGACGACGAGCTGGCAGGCGGCCCGGGAGGCGGCGCCGGGGGCCCAGGGGGCGGCCTGTA TGGAGAGCTCCCGGAGGGCACCTCCATCACCGTGGACTCCAAGCGCTTCTTCTTCGATGT GGGCTGCAACAAATACGGGGTGTTTCTGCGAGTGAGCGAGGTGAAGCCGTCCTACCGCAA TGCCATCACCGTACCCTTCAAAGCCTGGGGCAAGTTCGGAGGCGCCTTTTGCCGGTATGC GGATGAGATGAAAGAAATCCAGGAACGACAGAGGGATAAGCTTTATGAGCGACGTGGTGG GGGCAGCGGCGGCGGCGAAGAGTCAGAGGGTGAGGAGGTGGATGAGGATTGAAACGGGCA GCTTCCCCTACAGGCCTCCACCCAACCACCATCCCCTTGGCTAGAGAATTCCCTTTCCTG CTCATCCCCAGTGAGCTAGTGGAGAGGGAGCAAGGGAGGCCGCAGAGGGAAAAAACAAAA CGTAACACAGTTAAGAGAAATAATCGTAAGAGAACAGTGACGGACAACTTGAGAAAAGCA GTCAAGTTCCAAGGAACTGACAGCAACCTGCAAAGAGGAAAACAGCATCTCCTCACCTGC GTAAAATTGTCTCAGCTTCTGTTGTTTCTCAACTGAGGTTCGTAAACCCATCAGGATAAT CCCTGGAGGGAATAGATCCTTGCACATCCAGGGCAAGAAACATGTCCAAGTTACCCAGAC CATTGATAACAGTTGCATTTAGGTTGCACCTGGGTAATCTGGCATAAAAGATCTCTCTAG GCCTCACTGTTGCGGTGTCTATCCCTTCACCTCCATTGAAATCAGCATTTTGGATCTAGG TCTTCATGGAATCCTTGAGAAGAGAGGCCTTTACAATTACCCAGTTCTGAGGGTTCAGGT TCACGAAAAGAAATGCAACTTGGGATAATCATGAACAGGTTAAAGATAAGATTTCAAGAA GCCATCTAAGAATACAGAACCAAATTGGATCCATTTTTTTAAAAAAATGGTTTTGCATGG AACCTGGACCAAGGCAAATGTCTTTTCTTCGCAGAATTGTTTTCCAGGATGCCAGTGGAT TCAGATAGCAATGCTTGGAGTAGAATCCGTTACTAAAATAGTTTCAAAGTTGACAAAAAA TTTTCAAAGATAAAAGCAGTTTTACATTGGGGGTTGCTGAGGTAGGCACAAGAAAAAGTC AGGCATAAAGCACAAGGCAGACTGTTTGAGTGGATTGGTTGCTGCTCACTAAAGTTGTTC CCCTGATCTCTAAATATGGAGGTCATTACCAAGAAATGCTTTGGTATGAATGAGAGCCAG ATCTCCACTGTGTGAGCCAGTGAATTATGGCTAATTCGGCTGTTACAGCCACTGGTTGGC TGGATTTTAAACCATAAAACTTGAAGATTACCTACAAAAGTAACAGTGTGGCTATAAGCC TGAGCTTTAATGGATATACATCCTCACAGAAAAGTTGGAAATAACCAAAACTGAAGTCTT AATTTACCTTCAGTTTAATCTGTGGATTTGTTCAAATACTAAAGATCCTCAGGTCCAGAA TTCCAGCATCATTTATTCTTTTAAAATTTTTAAGAACTTGATCCATTGTATCAGTACCTC ACAATCAGAGTTGGCAAATGATGGATGAGTGATTCAAGCAGTGCACCCGGTGGAAGCTGA AATCCATCTGTGAATGGAACTGAAGTGAACGTGAATATGCTGACTATATCCTGGAAGCAT TTTTATACCATCTTGAAATTTCAACAAACTGGCTTTTGCCAGTTAATCCAGCTGTCTTTC AAGAATAAAAGTTGGGGTTTTCAAGGATCGCCTCTTCTATATTTTAAATGGATTTTCAGT AGAAATGATTTTTACTAATCAAGTTAATCCCACCCCATCAAAAGGTATTCCTAGAAATGT CATAGACCTAGGTAACTTTGAATTGAATGGGAGCTAACGTTCTTTCCAAAGTTTTCAGGT ATTCTTTGTGTGACACCTTCTCAACCAGGAGGCAAGTAACCCCGCCTCCACAATCTTAGT ATTTTTTTTAAACTGCATGCCTGCCCCTTATTTGAGCTGCCTTTTTAATTTATTGCATAT CCTTTTTATTATCTTATTTTGGTATTATTCAATCTATACAATCTTTTTGTATTTATTGGG AAATGAGTAATATACAAAAAGGTTTTCATGTATTTGTGGCTGAGAGGGCGGGAAATAATT GTGTACATAAAATTAGGCTTTTTTAAAAAAATAGATTATGATGCAGAATATTGTTGATCT TAGATTAAAAAGTGGAAGAGCCACAAACATTGGTGCCCTTTTCAGACTATTTCTCTACTC TCATCATCCACAGTAGAATTTTTAAACAGATTTTTTTAAAGCTTTTCTTTTAAATTTTTC TCCGTTGCAAAGAATGTTTCCTAAATTGTATGGGAGCAATAGTATTTTTGATGTTTTAAT GACATCCGTATACTTGTACTGTATTTTGTACTACAAGGCAGCTGTTTTTCAATAATGTCC TGCTGTATTTACCTACGTGTTTTGAGTGTCTATTTCTTTGCTGCGGAGAACAAATTCCTA AATAGTTTTAGTAAAGGAGCTGAGAAGCTAGCATTAGGTTTGCAGAAACTATTTAAGTTT CAACTCTGAGGCAGCAATGAAAATTTAAGTTGCAGCTATTAGTTGATTGCTGTAACTTTT TCATTTTCAAACCATGTACAATTCTTGTATAGACCAACTTGTTTTCTTGCTTCAGTGGTG GTTCTGTTGCTCAGCTGCAGTGAGCCAGTTCAATTTTGCAAAGGTGCAGTACCTCTCCTT TTTAAGGGGTTGGTTTATTCTTTTTTCTTTTTGTTTGGCTGAATTGCAGTAACTAGCCTT GCCTTTCTATTCTGTAGAAATGACAGGGTCTTCACAATCCTTCACCAGTGGCTACTAAGC TATAATTAGCTGAATAGAAAGAATGTGGAAGTGGTCTGAGGCATATAGAGTATATGCCAA GAACACTACCATATATGGCATCAGCTTTGGTTACCAGAGAAATTTTCTTAGTCATTAGAC CATGTAACAGTAATATATCATATGTAAATCTTTAGATATCAATTTGAAAATCCTCCAAAA AAAGGAGCAAAGAATGCATAAGCTATGTGTTGGCAAAAGTAATTTATATTAAAATTTTGA CCTGCCTATGTAAGATTAAGTGGTAATGTCATAGTGGTGGGTTTTTAAGTCTTAACCAAT CTCTAAGGTTTGTTTCTCCTGCAAGGGATGGTTCATGGCCTCTCTTCCCACTGCAGGAAG ATTGCAGAAGGCTGTGGATTAATTGTAGCATTTCACTGATCTTCACTCCAGTCACTAGGG ACAATAGAAACCTGCAAAACACAGATTCATTCGTAAATATTATTAATAGCTTATTAAAGG AAATGGTCTTTGTTAATTCCAGTCAGATAATGGCATTGTACAGACATGGGAAACAACCAA TTTTTTTGTTTTTCAGTTGTTGCTATGAATGATTTTGAGCCTTTTTTTTTAAGCTTGGCA AACATCCCAGCTAATCAAAATAGTCATATTCCTGAGAAGTAGGAAACTAAAACTTCTTTT CATATAATTGTTAGAAGGTTTGTTTCCCAAACTACCATAGTTACAAAGGTGAAAAGCCAA ATTTTAGGAACAGAATCAAAAGAATAAAAATCTGTGAAGAGATCCTACTACTCTTCCTTC TATGTTTTGGTTTTGGTTTCTATTGTCCCTATCATTTCAGCAAGTGGAACAGCAGCAAGT TTTTCAGTGCATATGCTGCACAAGAACAAAATATAAATCTGTATGGCACCAAAAATCAAA GTGAAAACCAAACCAAAAACCCAAACACCCTATGTAACTATCGGAGGCATATACGTGGTA TAAATGACTGTAGCTGTGATACACACATGGCTACTTGTCACATCACTTTCCATAATTATT TACTGCAAAATGATTGAGAGGCTTTTGGTGCAGGCAGCCGTTAACCTCCTGCTTCCTTTG TTACCTCTGGATTACTTTGCAGTAAATTGCAGGTCTTTTAAGAGATTTAAGCTTCAGTTT TCTCAAAACAAAACAATTATCCTGTCTTATCTGAAGATGCAGGGTTGTGGGCAAAAGAGG CTGGTTATAATAATGCCCTCATATTGAGTGGTCTGTAAACGGCTGCACACTTCAGGCACT GTAGTTGCTGAAGATGCTTTGTTAAATGTGACCTTGACTGGCTTTACAGGGGTGTAGAAT GTAATCTACACAAGGTGACTTTGCATCTATCTTGCTCTTGAGGTGGATGAAATTGAGAAG CTGGAGTGTGTAAGCCATGCACATAAGTATTCTTCACTGTAAATTTTGTTTTCATTTTTA ACCCAATTATGGTACTTTATCCAATGCACAACTGATCTCTCAGTAGATATTCATTTGAAA ATAGTGTGGCCTTGATCAGTGAGAAAGGGAAGGAGAAAAGTGACTTTTTTGCTTATGTAG AAATGACTCATTTGCTGAGAGTTTGTCTTTCTGCAGCACTCTTGGTATATAGTGATCGGT CTCCTTTTTGATTGGGGAAAGTTAATGTTTTTGACCCTGGAGTTAATTCAGTTGAGTTAT CTTATATTTTTAGGAAGTATCAGAATTGCTCTGATGAATAACAAAGTTGACTGTTTTGAT GTCCAATCTCAGGTTTTAGAATATAGTGGTGTAAAGTCCCACTATTTTTAATTCTTAAAA CAACTTTAATTTCGTACACCCTAAAAGTCACATGCATAAGGCCTGTTCAGAGAGCAGAGC CTCCATCTTTTTGCTCCTTTTCTACTTTGTACTTCACTTGAAAAAATATCAAGTGACTTT ACATTGTATATTTCCATTGTAACCCTGACATTTCTCAAAGATAAAGCACTTTTTGATCAT GAAATACATGAAATCTTTGTGTGATGTGGATCATAGTTTCTCAGGCTCCCTTAGATAATT GCTTATGAATATTGTTCTAACTCTGTGTAAGAAGAGTAGAAATCTTTGCTAATGTTAGAA GGTTTGTATTATTGATCCAGAATGCATTTTGCTAGTTTCCAATGGATGGGAGAGTAAATA ATGCTGCATTCACAATTTAATAAGTTACTTTCCCTTGAGCCTTAAGGTAACTTTTTCTTT CCTGTCAACTACAGCACTGAAGTTATAGTAAGTGAATGAGATTATCAGTTTTCAGGGTTG GTTTTAGAGTACTGTAAATCAATTAGCTGTCTTCCTAAAGAGTTACAACTCCCATTCAGT ATACTGGATAATGGGTGTGTGGGTGGGGCTGGGGAGGGCGGGAGATAGTTTGTAGAAAAG AAAAAAGAAAAAAAAAAAAACACATTTACCTTAAGAAAATACAGACAAAAAAGAATAAAG TATGTGTCATATGCTCCATTTGAGATTCCAAATGCGGCCGGGCGTGGTGGCTCACGCCTG TAATCCCAGCACTCTGGGAGGCTGAGGTGGGCGGGTCAGTTCAGGTCAGCCTGGACAACA TGGTGAAACCCCGTCTCTACTAAAAATACTAAAATTAGCCGGGCATGGTGGTGCATGCCT GTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAAGCGGAGG TTGCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGTAACAGAACAAGACTCCGT CTCAAAAAATAAATAAATAAATTCCAAATGTAAGGTGGAAATGGCAGATTATAACTTCAT TTCCCCCATTTTTAACTTAGAAAAAACAAAGTCCTTAATTTTCAAGTATTAGCCCCCCAG AAGTTTCAGCAGATAGCTGGACTCTTGAATAATGATTTCTTTTGATATGTCTGACTTTGC TATTTAAAGTCTCCTTTCCCAGCCCTCAGTCTTAAAACTCAGTTTTATTACTGACGGATT TAACAGACTCTTACTTGAAAATTGTCCAATTATCAGTACTGAAAATTAGATTTGGAAAAT GAAAAAATAATAAAATCGCATCAAGAAAACTTATTACCTTAGAGATTCCCAATTGATATC TGTACCCCTGATCCAAGTAAGGCCTTTATGAATGTATTTTATATTTCCTAAAGAAATAGG GAATATGCCATCAGTGTAATCACCTCTATTCACAGTCATTTAATTTGAAAATCTAACTCA TGTCTCTTGAATTAGACATTCCAATTGGGATAGGTAGAGTCATGTTAAAACAATAGAATA GCAACTGCCATATTGGTAGTTTCACTGCTCAATATGATTTCTAATAAGAGCAGAGCTTTA TTGGAAGCTAAAACTCATTTTTCTCCATAGATGATTCTAACAGTTTAATAAAAAAGTATA ATTATACTTTAAGTGTCAACAGATTTTGAGTCTAGAAGCAAATTTCATTTTCCTTGTGTT ATATCTAATATCCATTGACATGGGTAAGAAAACTAATTATGTCTTTTTAGTATGATGAAA TGTGGGCCCAGAGTATTGGAAAGAAAGCAATAGCCCTATTCAGTGTCCACTAGGATGGAT ATTGCAGAAGGCATGAGTTTGTCCTTTTTTCCCCCTTACCTTAAATAACACTTCAATAGC TAACTTTTTCCAAAATATCCATTTAGGCCATCTCTTATTTCTTAAAGCCAAATATTTCGT CCCCAGTCTTAACTCTGAGTTGCAAGATCAGGCTGGTTGGAAGAATCTTTATATTTAGAA ATAGGATGGTGAGTGGTTTGTTTATTCTCTTGTAAAATTCCTTTTTCAGAGACATAACTG CAGGGAGAGTCCCAAGAGAACTGAAGAACTGGATTATATCATTAAACACATTTGTGTTGT AGGAATTTGGGAGTTTCATTTTGAACTGATAAGATATTAGACATAAACCCTTGTTCCAGC CCACATGTGTCATCCCTGTGTACAAAAGCTCTCTGGATTCTTTTTTTTTTTTTGAGACGG AGTTTCGCTCTTATCGTCCAGGCTGGAGTGAGTGTAGTGGCTTGATCTCAGCTCACTGCA ACCTTTGCCTCCCGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTA CAAGCATGTGCCACCATGCCCAGCTAATTTTCTGTATTTTTAGTAGAGACGGGGTTTCAC CATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCCGCCTCAGCTTCC CAAAATGCTGGAATTACAGGCATGAGCCATCACGCCTAGCCTACTCTCTGAATTTCTAAA AGTCAGTAGGTTGACCAAAAAGTCTAGAAACTGGCTTTAAGTCAGTATGGGACGTACTTA TAAAGAGTCCATGGTTTTGCACGTTTCGGTAGACAAGTAAATCTGAGTTATTTTTCAATG ACTTACCAATATTTGAATAGTAACTAAGATCGTCAGTGTATCTGGACTTCTTTTTTTGAA GTTCTAAAACAATTATAGTAGGGATTTATTATTTTGGGCCTCCATCCAGATGTTTTTCCA AGATCATTTTTAAAATTCATTTGTCTTCTGTTTCCAGATAACATACTTTCCGTTCTATAG GAATCTTCACTGCCAATCATAGTATCTACCAGTGGCTTTCTTAGACTATTCACTCCAAAG CTGGGACTGATGTCCTGCCAGTAGAGAATCTACAGAAATAATTTGAATGAATTAAAACCA AATCTTGATAGCAGGAGACAGCTTCCTGATCTAGATGTACAATTAGAGTTTAGGTTGGAA ATTACTTTAAAATGTGTTTTTTGGGGATGTCTTCAATCTCTGTGTAAATACCCACATGCT TATGCATTGTAAACCAAGTGTGTATTCCTGTGTATGAATTTGTAGAACTGATTTCTGCTT CAAGAGAAGCTGCACCTTTAATTTTATAAGGTCCCCTCCACCTGTAACCCTATAAATGTC TGTAAATAAAACACTAAAATTTGTAGTGATAGGATCAATTTGGGAATATCTGCTGAGAGA CCAAAAAGTTCATTTTTTTAAGTACCTTGGTTAAAGAGTAAAGATTATTCCTCTTATTTT TTAAAGAAGAATGCACTTTAACAAACATAGAGCTGCATGGGCAATTCAAACAAATCTGTG AAGTGCAGTACCCATTCAGAAATCACACTTCCTGAAAACCGTTCAAAAGCAGAGTCCAGA CGGGCTGTTGATCTCACTGCCTGTAGGTTGAAGCTCAGATTCTGATCAATTTTGAGAGGA GCAGGGCTGCTTCAAAAGAGCAATGTGAATACAGTCAGAAGCTTCAGACTGGTCTGTAAA AATGGCGGGTCCCGTATTTACCACTAACTAGCAAAACTGACAGAAAAACTCACAGAGAAA AAATGTAAGAATCCTTCCTGCTGGTGTGCACTCCTTACAATAGACTTTTGCAAATGGAGT TTTACAGTCTATATTTAAAAAAAATTGTATGTTTGTAACAAATAAAGTATGCAGAAAAGT GAATGACAA OMIM ID 608887