Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PVRL2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5819
Official gene symbolPVRL2
Full namepoliovirus receptor-related 2 (herpesvirus entry mediator B)
Aliases,CD112,HVEB,PRR2,PVRR2,
Gene summaryThis gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.2
Gene position45349393 - 45392485  Map Viewer
Gene orientationplus
Gene size43093 bp
Gene sequence
OMIM ID600798